The urologist’s learning curve of “in-bore” magnetic resonance-guided prostate biopsy

BMC Urology

Table 1 Patient characteristics and MRI imaging findings

Variable		All		Untrained		Trained		p value
Age	Median, IQR	68	62–72	68	62–72	67	62.5–72.5	0.68
PSA (ng/dL)	Mean, STD	8.6	9.1	8.6	9.9	8.7	8.3	0.95
Prostate size (cc)	Mean, STD	53	27	53	27	56	52	0.72
PSA density (ng/dL/cc)	Mean, STD	0.20	0.30	0.22	0.37	0.15	0.10	0.31
Previous biopsy	Number, %	76	70	34	63^*	42	76	0.13
Number of target lesions on MRI	Mean, STD	1.47	0.6	1.44	0.6	1.51	0.6	0.54
MRI target lesions’ characteristics
PI-RADS 3	Number, %	84	51.9	38	48.1	46	55.4	0.43
PI-RADS 4	Number, %	62	38.3	34	43.0	28	33.7	0.26
PI-RADS 5	Number, %	16	9.9	7	8.9	9	10.8	0.79
Lesion size (mm)	Median, IQR	7	5–11	7.5	6–11	7	4–12	0.4
Large lesion size (mm)	Mean, STD	10	6	10	6	9	6	0.63
Small lesion size (mm)	Mean, STD	8	6	9	6	7	4	0.095
Lesion location—Base^#	Number, %	27	17	10	13	17	20	0.2
Lesion location—Mid-gland^#	Number, %	91	56	39	49	52	63	0.11
Lesion location—Apex^#	Number, %	56	35	30	38	26	31	0.4
Number of targeted cores/lesion	Mean, STD	3.3	1.6	3.0	1.1	3.6	1.9	0.07

Untrained urologist with no experience in performing IB-MRGpBs, Trained urologist highly trained in performing IB-MRGpBs, Large lesion size represents the size of the larger lesion when more than 1 target lesion was identified on pre-biopsy imaging, Small lesion size represents the size of the smaller lesion when more than 1 target lesion was identified on pre-biopsy imaging, PSA prostate-specific antigen, STD standard deviation, IQR interquartile range, PI-RADS prostate imaging reporting and data system v.2, MRI magnetic resonance imaging
*One patient had no available data regarding former biopsy
^#Percentages calculated per total number of lesions. Numbers may not add up due to overlap with some lesions located in more than one anatomical section (e.g. base-mid etc.’)

ISSN: 1471-2490