Fig. 3From: Intravesical ichthyosis: a rare case reportIchthyosis vesicae. Diffuse keratinizing squamous metaplasia was seen in nearly all biopsies (25 ×, HE) with orthokeratosis, papillomatosis, hypergranulosis of the squamous epithelium and partly vacuolated keratinocystes (koilocytes) but without nuclear atypia (50 × & 200 ×, HE)Back to article page