Clinically significant prostate cancer (csPCa) detection with various prostate sampling schemes based on different csPCa definitions

Table.4 Associated predictors of Gleason score upgrading on ipsi-SB + TB

		38 upgrading			14 significantly upgrading
	OR	95% CI	P value	OR	95% CI	P value
TRUS prostate volume (per 10 volume)	0.970	0.950–0.990	0.004	0.980	0.950–1.012	0.022
Biopsy history (yes or no)	2.365	0.903–6.192	0.008	–	–	–
Location (PZ or TZ)	1.949	0.713–5.324	0.019	8.424	1.201–59.065	0.032
PSA (per ng/mL)	1.001	0.999–1.004	0.028	–	–	–

Statistically significant at P < 0.05. SB, systematic biopsy; TB, targeted biopsy; ipsi-SB, ipsilateral SB; OR, odds ratio; CI, confidence interval; TRUS, transrectal ultrasound; PZ, peripheral zone; TZ, transitional zone; PSA, prostate-specific antigen

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