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Table 2 Results for p16 staining, Sanger sequencing and LCD-Array technique for squamous cell carcinomas, carcinoma in situ (Cais) and non-tumor tissue as well as overall

From: The routine use of LCD-Array hybridisation technique for HPV subtyping in the diagnosis of penile carcinoma compared to other methods

Sample

p16

Sanger sequencing

LCD-Array technique

positive (%)

negative (%)

positive (%)

negative (%)

positive (%)

negative (%)

Squamous cell carcinomas (n = 62)

32/62 (52%)

30/62 (48%)

16/61 (26%)

45/61 (74%)

34/60 (57%)

26/60 (43%)

Cais (n = 6)

4/6 (67%)

2/6 (33%)

1/6 (17%)

5/6 (83%)

6/6 (100%)

0 (0%)

non-tumor tissue (n = 69)

3/68 (4%)

65/68 (96%)

4/68 (6%)

64/68 (94%)

18/66 (27%)

48/66 (73%)

Overall (n = 139)

39/138 (28%)

99/138 (72%)

21/137 (15%)

116/137 (85%)

58/134 (43%)

76/134 (57%)

  1. Extramammary Paget disease, focally invasive and basal cell carcinoma were negative for p16 staining, and showed no HPV infection via Sanger sequencing and LCD-Array technique