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Table 1 Characteristics of patients with histopathologically diagnosed T1 HG bladder cancers

From: Biological distinction between grades 2 and 3 with respect to intravesical recurrence in T1 high-grade bladder tumors: a retrospective study

Groups parameter Total (n = 145) With Ins Without Ins p value
(1) (2) (3)
G2 (n = 6) G3 (n = 70) G2 (n = 32) G3 (n = 37)
Sex, n (%)       
 Male 117 (81) 6 (100) 57 (81) 27 (84) 27 (73)  
 Female 28 (19) 0 (0) 13 (19) 5 (16) 10 (27) 0.4105
Age       
 Median (min–max) (yr) 74 (32–89) 75 (56–86) 73 (47–89) 74 (57–87) 76 (32–88) 0.5777
 < 70, n (%) 54 (37) 2 (33) 27 (39) 9 (28) 16 (43)  
 70, n (%) 91 (63) 4 (67) 43 (61) 23 (72) 21 (57) 0.4230
Number of tumors, n (%)       
 Single 52 (36) 2 (33) 22 (31) 14 (44) 14 (38)  
 Multiple 93 (64) 4 (67) 48 (69) 18 (56) 23 (62) 0.4639
Maximum diameter, n (%)       
 < 3 cm 116 (80) 5 (83) 54 (77) 27 (84) 30 (81)  
 3 cm 29 (20) 1 (17) 16 (23) 5 (16) 7 (19) 0.7623
History of recurrence, n (%)       
 Primary 103 (71) 3 (50) 54 (77) 17 (53) 29 (78)  
 Recurrent 42 (29) 3 (50) 16 (23) 15 (47) 8 (22) 0.0492
Concomitant CIS, n (%)       
 No 111 (77) 5 (83) 43 (61) 31 (97) 32 (86)  
 Yes 34 (23) 1 (17) 27 (39) 1 (3) 5 (14) 0.0001
WHO grade 1973, n (%)       
 G2 38 (26) 6 (100) 0 (0) 32 (100) 0 (0)  
 G3 107 (74) 0 (0) 70 (100) 0 (0) 37 (100) < 0.0001
Second TURBT, n (%)       
 No 46 (32) 2 (33) 10 (14) 24 (75) 10 (27)  
 Yes 99 (68) 4 (67) 60 (86) 8 (25) 27 (73) < 0.0001
Ins in a series, n (%)       
 No 69 (48) 0 (0) 0 (0) 32 (100) 37 (100)  
 Yes 76 (52) 6 (100) 70 (100) 0 (0) 0 (0) < 0.0001
Ins in whole lifetime, n (%)       
 No 60 (41) 0 (0) 0 (0) 29 (91) 31 (84)  
 Yes 85 (59) 6 (100) 70 (100) 3 (9) 6 (16) < 0.0001
  1. HG high grade, Ins intravesical instillation therapy, G2 grade 2, G3 grade 3, CIS carcinoma in situ, TURBT transurethral resection of bladder tumor