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Table 1 Characteristics of patients with histopathologically diagnosed T1 HG bladder cancers

From: Biological distinction between grades 2 and 3 with respect to intravesical recurrence in T1 high-grade bladder tumors: a retrospective study

Groups parameter

Total (n = 145)

With Ins

Without Ins

p value

(1)

(2)

(3)

G2 (n = 6)

G3 (n = 70)

G2 (n = 32)

G3 (n = 37)

Sex, n (%)

      

 Male

117 (81)

6 (100)

57 (81)

27 (84)

27 (73)

 

 Female

28 (19)

0 (0)

13 (19)

5 (16)

10 (27)

0.4105

Age

      

 Median (min–max) (yr)

74 (32–89)

75 (56–86)

73 (47–89)

74 (57–87)

76 (32–88)

0.5777

 < 70, n (%)

54 (37)

2 (33)

27 (39)

9 (28)

16 (43)

 

 70, n (%)

91 (63)

4 (67)

43 (61)

23 (72)

21 (57)

0.4230

Number of tumors, n (%)

      

 Single

52 (36)

2 (33)

22 (31)

14 (44)

14 (38)

 

 Multiple

93 (64)

4 (67)

48 (69)

18 (56)

23 (62)

0.4639

Maximum diameter, n (%)

      

 < 3 cm

116 (80)

5 (83)

54 (77)

27 (84)

30 (81)

 

 3 cm

29 (20)

1 (17)

16 (23)

5 (16)

7 (19)

0.7623

History of recurrence, n (%)

      

 Primary

103 (71)

3 (50)

54 (77)

17 (53)

29 (78)

 

 Recurrent

42 (29)

3 (50)

16 (23)

15 (47)

8 (22)

0.0492

Concomitant CIS, n (%)

      

 No

111 (77)

5 (83)

43 (61)

31 (97)

32 (86)

 

 Yes

34 (23)

1 (17)

27 (39)

1 (3)

5 (14)

0.0001

WHO grade 1973, n (%)

      

 G2

38 (26)

6 (100)

0 (0)

32 (100)

0 (0)

 

 G3

107 (74)

0 (0)

70 (100)

0 (0)

37 (100)

< 0.0001

Second TURBT, n (%)

      

 No

46 (32)

2 (33)

10 (14)

24 (75)

10 (27)

 

 Yes

99 (68)

4 (67)

60 (86)

8 (25)

27 (73)

< 0.0001

Ins in a series, n (%)

      

 No

69 (48)

0 (0)

0 (0)

32 (100)

37 (100)

 

 Yes

76 (52)

6 (100)

70 (100)

0 (0)

0 (0)

< 0.0001

Ins in whole lifetime, n (%)

      

 No

60 (41)

0 (0)

0 (0)

29 (91)

31 (84)

 

 Yes

85 (59)

6 (100)

70 (100)

3 (9)

6 (16)

< 0.0001

  1. HG high grade, Ins intravesical instillation therapy, G2 grade 2, G3 grade 3, CIS carcinoma in situ, TURBT transurethral resection of bladder tumor