Fig. 3
From: FOXO3a-ROS pathway is involved in androgen-induced proliferation of prostate cancer cell
Activating androgen receptor decrease the expression of FOXO3a and catalase in LNCaP cells. A DHT treatment promoted proliferation in LNCaP and 22RV1 cells by CCK8 assay. B FOXO3a and catalase expression decreased in LNCaP cells which was treated with DHT. C FOXO3a and catalase expression were not change in 22RV1 cells which was treated with DHT. D DHT treatment down-regulated the expression of FOXO3a and catalase at protein level in LNCaP cells. (*p < 0.05, **p < 0.01, ***p < 0.001)