Fig. 4
From: FOXO3a-ROS pathway is involved in androgen-induced proliferation of prostate cancer cell
The effect of over-expression of FOXO3a and knockdown of FOXO3a on the catalase expression in LNCaP cells. A Over-expression of FOXO3a increased the expression of FOXO3a and catalase after DHT treatment in LNCaP cells. B, C FOXO3a siRNAs transfection can decrease the elevated expression of FOXO3a and catalase at mRNA and protein level after DHT treatment and over-expression of FOXO3a. Control OE, over-expressing control vector; FOXO3a OE, FOXO3a over-expressingvector; NC, negative control siRNA; siRNA1, first FOXO3a-specific siRNA; siRNA2, second FOXO3a-specific siRNA. (*p < 0.05, **p < 0.01, ***p < 0.001)