|
Variable
|
Category
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
HR
|
95% CI
|
P value
|
HR
|
95% CI
|
P value
|
|---|
|
Age
|
≥ 70
|
1.04
|
0.66–1.66
|
0.86
|
1.37
|
0.82–2.28
|
0.23
|
|
≤ 69
|
1.0
| | |
1.0
| | |
|
Sex
|
Female
|
1.36
|
0.80–2.30
|
0.25
|
1.51
|
0.82–2.79
|
0.19
|
|
Male
|
1.0
| | |
1.0
| | |
|
T stage
|
≥ pT3
|
1.47
|
0.88–2.46
|
0.14
|
1.92
|
1.06–3.46
|
0.03
|
|
≤ pT2
|
1.0
| | |
1.0
| | |
|
Metastasis
|
|
Liver
|
Positive
|
1.68
|
1.02–2.77
|
0.041
|
2.13
|
1.17–3.85
|
0.01
|
|
Negative
|
1.0
| | |
1.0
| | |
|
Lung
|
Positive
|
1.21
|
0.72–2.05
|
0.47
|
1.57
|
0.85–2.91
|
0.15
|
|
Negative
|
1.0
| | |
1.0
| | |
|
Lymph node
|
Positive
|
0.89
|
0.56–1.42
|
0.63
|
0.90
|
0.53–1.52
|
0.69
|
|
Negative
|
1.0
| | |
1.0
| | |
|
Bone
|
Positive
|
0.89
|
0.53–1.48
|
0.66
|
0.90
|
0.48–1.69
|
0.75
|
|
Negative
|
1.0
| | |
1.0
| | |
|
AC
|
Positive
|
0.76
|
0.46–1.24
|
0.27
|
0.53
|
0.27–1.03
|
0.06
|
|
Negative
|
1.0
| | |
1.0
| | |
|
SC
|
Positive
|
0.67
|
0.42–1.07
|
0.096
|
0.72
|
0.40–1.29
|
0.27
|
|
Negative
|
1.0
| | |
1.0
| | |
- HR hazard ratio, CI confidence interval, TTR time to recurrence, RC radical cystectomy, AC adjuvant chemotherapy, SC salvage cytotoxic chemotherapy
