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Table 4 Association of tumor PD-L1 and B7-H3 expression with clinicopathological features

From: Evaluation of PD-L1 and B7-H3 expression as a predictor of response to adjuvant chemotherapy in bladder cancer

Feature

Tumor PD-L1 expression

P*

Tumor B7-H3 expression

P*

High (n = 8)

Low/negative (n = 73)

High (n = 17)

Low/negative (n = 64)

Age

  

0.932

  

0.818

 Mean (SD)

61 (7.1)

61.3 (9.9)

 

61.4 (7.7)

60.8 (10.5)

 

 Median

61.9

61.6

 

60.6

62.7

 

Gender

  

0.677

  

0.345

 Male

7 (87.5%)

56 (76.7%)

 

15 (88.2%)

49 (76.6%)

 

 Female

1 (12.5%)

17 (23.3%)

 

2 (11.8%)

15 (23.4%)

 

Tumor stage

  

0.424

  

0.242

 ≤ T2b

1 (87.5%)

24 (32.9%)

 

3 (17.6%)

22 (34.4%)

 

 ≥ T3a

7 (12.5%)

49 (67.1%)

 

14 (82.4%)

42 (65.6%)

 

LN status

  

0.084

  

0.351

 Positive

5 (62.5%)

63 (86.3%)

 

13 (76.5%)

55 (85.9%)

 

 Negative

3 (37.5%)

10 (13.7%)

 

4 (23.5%)

9 (14.1%)

 

Histological type

  

0.352

  

0.054

 Pure UC

8 (100%)

61 (83.7%)

 

17 (100%)

52 (81.3%)

 

 Other subtypes

0 (0%)

12 (16.4%)

 

0 (0%)

12 (18.7%)

 
  1. LN Lymph node, UC urothelial carcinoma
  2. *P values by Fisher’s exact test: *p < 0.05, **p < 0.01, ***p < 0.001