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Table 3 Multivariate survival analysis in patients

From: Evaluation of cystoprostatectomy on patients with prostate cancer extending to bladder: a retrospective study from single center

 

PCSS

PFS

HR (95% CI)

P value

HR (95% CI)

P value

Preoperative PSA (ng/ml)

 ≤ 20

Reference

 

Reference

 

 > 20

1.85 (0.76–3.88)

0.163

2.08 (0.88–3.05)

0.219

Gleason scorea

 ≤ 6

Reference

 

Reference

 

7

1.15 (0.74–2.16)

0.061

2.28 (1.19–3.96)

0.029

 ≥ 8

2.55 (1.28–4.04)

0.033

1.96 (1.33–3.89)

0.026

Therapeutic methods

Neo CAB + Post ADT

Reference

 

Reference

 

Neo CAB + Post ADT + Post Che

1.57 (0.63–2.63)

0.673

0.96 (0.90–1.38)

0.363

Neo CAB + Post ADT + Post Rad

2.89 (0.55–5.01)

0.419

1.42 (0.79–1.78)

0.186

Neo Che + Post ADT + Post Che

1.80 (0.79–2.61)

0.309

1.17 (1.02–2.71)

0.041

Local lymph node statusa

pN0

Reference

 

Reference

 

pN1

3.52 (1.57–7.38)

0.006

2.60 (1.47–3.38)

0.011

Seminal vesicle statusa

Negative

Reference

 

Reference

 

Positive

2.16 (0.76–5.04)

0.266

0.89 (0.61–1.58)

0.068

Surgical marginsa

Negative

Reference

 

Reference

 

Positive

1.26 (0.58–2.51)

0.075

2.24 (0.58–3.06)

0.421

Invasion depth of bladder walla

Non-muscle-invasion

Reference

 

Reference

 

Muscle-invasion

4.75 (1.37–7.53)

 < 0.001

1.46 (1.06–3.02)

0.020

  1. aThese issues were determined by postoperative pathological analyses. ADT, androgen deprivation therapy; Che, chemotherapy; CI, confidence interval; HR, hazard ratio; CAB, maximal androgen blockade; Neo, neoadjuvant; PCSS, prostate cancer-specific survival; PFS, PSA recurrence-free survival; Post, postoperative; PSA, prostate-specific antigen; Rad, radiation therapy