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Table 1 Patient demographics and baseline characteristics

From: Tislelizumab in combination with gemcitabine plus cisplatin chemotherapy as first-line adjuvant treatment for locally advanced or metastatic bladder cancer: a retrospective study

 

TGC (n = 14)

GC (n = 17)

p value

Age, years

 < 65

6 (42.9)

7 (41.2)

0.93

 ≥ 65

8 (57.1)

10 (58.8)

 

Gender

Male

10 (71.4)

12 (70.6)

0.96

Female

4 (28.6)

5 (29.4)

 

Tobacco use

Never

5 (35.7)

7 (41.2)

0.77

Current or former

9 (64.3)

10 (58.8)

 

ECOG status

0

7 (50)

9 (52.9)

0.88

1

7 (50)

8 (47.1)

 

Disease status

Locally advanced

4 (28.6)

6 (35.3)

0.70

Metastatic

10 (71.4)

11 (64.7)

 

Site of metastatic disease

Lymph nodes only

2 (14.3)

2 (11.8)

0.86

Viscerala ± lymph nodes

3 (21.4)

3 (17.6)

 

Multiple metastatic sites

5 (35.7)

6 (35.3)

 

PD-L1 expression

TC < 50% and IC <  50%

6 (42.9)

8 (47.1)

0.73

TC ≥ 50% or IC ≥ 50%

2 (14.3)

3 (17.6)

 

Unknown

6 (42.9)

6 (35.3)

 
  1. TGC tislelizumab plus gemcitabine and cisplatin, GC gemcitabine and cisplatin, CI confidence interval, ECOG Eastern Cooperative Oncology Group performance score, PD-L1 programmed death ligand 1, TC tumor cell, IC immune cell
  2. aDefined as one among of lung, liver, and bone metastases