Skip to main content

Table 1 Patients characteristics

From: Enzalutamide in patients with non-metastatic castration-resistant prostate cancer after combined androgen blockade for recurrence following radical treatment in Japan (Japanese research for patients with non-metastatic castration-resistant prostate cancer-enzalutamide: JCASTRE-zero)—a prospective single-arm interventional study

   

N = 64

 

Age

years

   

 Mean (SD)

  

75.4

6.5

 Median

  

76

 

 Range

  

58–90

 

ECOG performance-status

No. (%)

   

 0

  

63

98.4

 1

  

1

1.6

TNM classification (cT)

No. (%)

T1a

1

1.6

  

T1c

7

10.9

  

T2a

10

15.6

  

T2b

5

7.8

  

T2c

9

14.1

  

T3a

19

29.7

  

T3b

9

14.1

  

T4

2

3.1

  

TX

2

3.1

TNM classification (cN)

No. (%)

N0

60

93.8

  

N1

3

4.7

  

NX

1

1.6

Gleason score

No. (%)

 ≤ 6

8

12.5

  

7

18

28.1

  

8 ≤ 

38

59.4

Serum testosterone

ng/dL

   

 Mean (SD)

  

11.85

11.37

 Median

  

10

 

 Range

  

0.03–47

 

Serum PSA

ng/mL

   

 Mean (SD)

  

6.7

7.66

 Median

  

3.95

 

 Range

  

1.03–35.13

 

History of radical prostatectomy

  

29

45.3

 With endocrine therapy

  

14

48.3

 TNM classification (pT)

T1c

 

1

3.4

 

T2a

 

3

10.3

 

T2b

 

4

13.8

 

T2c

 

3

10.3

 

T3a

 

6

20.7

 

T3b

 

8

27.6

 

T4

 

2

6.9

 

TX

 

2

6.9

 TNM classification (pN)

N0

 

24

82.8

 

N1

 

3

10.3

 

NX

 

2

6.9

 Gleason score

 ≤ 6

 

1

3.4

 

7

 

8

27.6

 

8 ≤ 

 

19

65.5

 

Missing

 

1

3.4

History of radiation therapy

Yes

 

48

75.0

 

EBRT

 

43

89.6

 

Brachytherapy

 

4

8.3

 

EBRT + Brachytherapy

 

1

2.1

 

with endocrine therapy

 

27

56.3

History of bilateral orchiectomy

  

1

1.6

History of GnRH analogue use

  

63

98.4

History of bicalutamide use

  

64

100

 Median administration period

day

 

715

 

 AWS

yes

 

46

71.9

History of flutamide use

  

23

35.9

 Median administration period

day

 

330

 

 AWS

yes

 

16

25.0

  1. AWS Antiandrogen withdrawal syndromes; cN Clinical lymph nodes classification; cT Clinical tumor classification; EBRT External beam radiotherapy; ECOG Eastern cooperative oncology group; GnRH Gonadotropin-releasing hormone; pN Pathological lymph node classification; PSA Prostate-specific antigen; pT Pathological tumor classification; SD Standard deviation