Fig. 9

Correlation between CDH1 expression and immune cell infiltration in BC and the ceRNA network construction. A Relationships among infiltration levels of 24 immune cell types and CDH1 expression profiles in BC samples based on the TCGA database by Spearman correlation analysis. B The infiltration levels of the 24 immune cell types were evaluated in distinct CDH1 groups in BC samples. ns, P > 0.05; *P < 0.05; **P < 0.01; ***P < 0.001. DCs, dendritic cells; aDCs, activated DCs; iDCs, immature DCs; pDCs, plasmacytoid DCs; NK, natural killer cells; Th, T helper cells; Th1, type 1 Th cells; Th2, type 2 Th cells; Th17, type 17 Th cells; Tcm, T central memory cells; Tem, T effector memory cells; Tfh, T follicular helper cells; Tgd, T gamma delta cells; Treg, regulatory T cells. C ceRNA network containing hub genes, differently expressed miRNAs and lncRNAs in BC. D ceRNA network associated with CDH1. Larger circular nodes represent mRNA, smaller circular nodes represent miRNA, and hexagonal nodes represent lncRNA