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Table 3 Coefficients for the nine genes in the optimal risk model for survival of bladder cancer patients

From: CDH1 overexpression predicts bladder cancer from early stage and inversely correlates with immune infiltration

Gene symbol

Description

Coefficient

P-value

UBE2C

Ubiquitin Conjugating Enzyme E2 C

− 0.23099

8.88E-03

FASN

Fatty Acid Synthase

0.31633

5.71E-04

SPAG4

Sperm Associated Antigen 4

0.16882

1.49E-01

FCRLB

Fc Receptor Like B

0.10812

1.02E-01

FER1L4

Fer-1 Like Family Member 4

− 0.35367

7.57E-05

EPN3

Epsin 3

− 0.13823

1.18E-01

UPK2

Uroplakin 2

0.11497

2.53E-03

CTSE

Cathepsin E

− 0.09189

6.96E-02

TOX3

TOX High Mobility Group Box Family Member 3

− 0.10033

1.39E-01

  1. Risk score = UBE2C × (− 0.231) + FASN × (0.316) + SPAG4 × (0.169) + FCRLB × (0.108) + FER1L4 × (-0.354) + EPN3 × (− 0.138) + UPK2 × (0.115) + CTSE × (− 0.092) + TOX3 × (− 0.100)
  2. Likelihood ratio test = 82.23 on 9 df, p = 5.83e-14, n = 530
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BMC Urology

ISSN: 1471-2490

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