Table 1 Association of clinicopathological characteristics with overall survival using univariate or multivariate Cox regression analysis
From: High CENPA expression in papillary renal cell carcinoma tissues is associated with poor prognosis
Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
Age | 286 | ||||
< = 60 | 133 | Reference | |||
> 60 | 153 | 0.944 (0.519–1.718) | 0.851 | ||
Gender | 288 | ||||
Male | 211 | Reference | |||
Female | 77 | 1.567 (0.813–3.021) | 0.180 | ||
Race | 272 | ||||
White | 205 | Reference | |||
Black or African American | 61 | 0.935 (0.413–2.116) | 0.871 | ||
Asian | 6 | 5.966 (0.769–46.311) | 0.088 | ||
Height | 212 | ||||
< = 170 | 87 | Reference | |||
> 170 | 125 | 0.328 (0.155–0.696) | 0.004 | 0.000 (0.000–0.000) | < 0.001 |
Weight | 218 | ||||
< = 80 | 83 | Reference | |||
> 80 | 135 | 0.413 (0.207–0.827) | 0.013 | 0.000 (0.000–0.000) | < 0.001 |
Laterality | 285 | ||||
Left | 159 | Reference | |||
Right | 126 | 0.735 (0.392–1.376) | 0.335 | ||
Primary therapy outcome | 199 | ||||
CR | 185 | Reference | |||
PD & SD & PR | 14 | 7.157 (3.084–16.612) | < 0.001 | 0.000 (0.000–0.001) | < 0.001 |
Pathologic T stage | 286 | ||||
T1 & T2 | 225 | Reference | |||
T3 & T4 | 61 | 5.121 (2.790–9.397) | < 0.001 | 76,417,798,304,913,744.000 (7,520,202,477,862,371.000–776,532,269,571,339,520.000) | < 0.001 |
Pathologic N stage | 77 | ||||
N0 | 49 | Reference | |||
N1 & N2 | 28 | 5.003 (2.062–12.140) | < 0.001 | 0.000 (0.000–0.000) | < 0.001 |
Clinical stage | 198 | ||||
Stage I & stage II | 159 | Reference | |||
Stage III & stage IV | 39 | 9.489 (4.596–19.592) | < 0.001 | 1.000 (0.098–10.162) | 1.000 |
CENPA | 288 | ||||
Low | 144 | Reference | |||
High | 144 | 3.102 (1.597–6.028) | < 0.001 | 282,613,493.616 (27,811,723.552–2,871,824,416.970) | < 0.001 |