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Table 6 Genetic analysis of potential therapeutic target genes of aspirin in bladder cancer

From: The targets of aspirin in bladder cancer: bioinformatics analysis

Gene

symbol

Gene name

GO term

Gene function

GSK3B

Glycogen synthase kinase-3 beta

GO:0090090

negative regulation of canonical Wnt signaling pathway

CDC20

Cell division cycle protein 20 homolog

GO:0008054

anaphase-promoting complex-dependent catabolic process

TPX2

Targeting protein for XKLP2

GO:0008017

microtubule binding

AURKA

Aurora kinase A

GO:0032465

regulation of cytokinesis

CCNE1

G1/S-specific cyclin-E1

GO:0000079

regulation of cyclin-dependent protein serine/threonine kinase activity