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Fig. 2 | BMC Urology

Fig. 2

From: Upregulation of mir-1199-5p is associated with reduced type 2 5-α reductase expression in benign prostatic hyperplasia

Fig. 2

Prediction and screening of miRNA. (A) Venn diagram showed that 39 miRNAs were predicted to binding 3’UTR of SRD5A2 by miRWalk (http://mirwalk.umm.uni-heidelberg.de/) and miRDB (http://mirdb.org) database. (B)The RT-qPCR results showed that only the expression of miR-1199-5p in BPH-1 was significantly higher than that in RWPE-1. (C) The relative expression of miR-1199-5p in tissues with negative SRD5A2 expression, weak SRD5A2 expression, and positive SRD5A2. *P<0.05;***P<0.001;miRNA: microRNA; SRD5A2: 5-α reductase type 2; BPH: benign prostate hyperplasia; BPH-1: immortalized benign prostatic hyperplasia epithelial cells; RWPE-1: normal prostate epithelial cell line

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BMC Urology

ISSN: 1471-2490

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