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Table 2 Sensitivity, specificity, PPV, and NPV of UTC assay and FISH

From: Diagnostic performance of an immunoassay based on urine exfoliated cell enrichment nanotechnology for upper tract urothelial carcinoma: a retrospective, monocentric study

 

UTC assay

FISH

P value

 

No. accuracy/Total (%)

No. accuracy/Total (%)

Stage

   

Non-MI (pTa, pTis, pT1)

23/26 (88.5)

16/26 (61.5)

0.025

MI (pT2-T4)

28/34 (82.4)

28/34 (82.4)

ns.

Grade

   

Low

7/8 (87.5)

3/8 (37.5)

0.119

High

44/52 (84.6)

41/52 (78.8)

0.446

Overall sensitivity

51/60 (85)

44/60 (73.3)

0.116

Overall specificity

37/40 (92.5)

38/40 (95)

ns.

PPV

51/54 (94.4)

44/46 (95.7)

ns.

NPV

37/46 (80.4)

38/54 (70.4)

0.247

  1. FISH = fluorescence in situ hybridization; MI = muscle invasive; PPV = positive predictive value; NPV = negative predictive value; ns. = non-significant