Table 1 Results of mice in pBOO and control groups at 8 weeks after operation
Items | pBOO group (n = 8) | Control group (n = 8) | P value |
|---|---|---|---|
12-h urination frequency | 7.63 ± 1.19 | 4.13 ± 0.99 | < 0.001 |
12-h urination volume (µL) | 1491.23 ± 94.72 | 1344.86 ± 88.17 | 0.006 |
Body weight of the mice (g) | 26.54 ± 2.62 | 24.84 ± 1.76 | 0.15 |
Bladder weight (mg) | 53.16 ± 1.79 | 24.54 ± 1.80 | < 0.001 |
Bladder horizontal length (mm) | 5.76 ± 0.32 | 3.01 ± 0.22 | < 0.001 |
Bladder vertical length (mm) | 4.94 ± 0.23 | 3.56 ± 0.37 | < 0.001 |
Detrusor thickness (µm) | 357.50 ± 11.88 | 258.52 ± 17.22 | < 0.001 |
Detrusor strips contraction to carbachol (3 × 10−8 M) | 170.75 ± 9.16 | 1.25 ± 0.46 | < 0.001 |
Detrusor strips contraction to carbachol (1 × 10−7 M) | 213.00 ± 12.66 | 79.38 ± 7.98 | < 0.001 |
Detrusor strips contraction to carbachol (3 × 10−7 M) | 317.63 ± 27.99 | 180.51 ± 11.36 | < 0.001 |