Variables | Rapid SCr trajectory (≥ 0.3 mg/dL/day) (n = 64) | Slow SCr trajectory (< 0.3 mg/dL/day) (n = 38) | p value |
---|---|---|---|
Mean ± SD (Range; IQR) at 95% CI or Number (Percentage) | |||
Age (year) | 58.3 ± 15.8 (24–86; 54.4–62.3) | 61.7 ± 12.9 (23–82; 57.5–65.9) | 0.544 |
Gender | |||
Men | 41 (64.1%) | 32 (84.2%) | 0.051 |
Women | 23 (35.9%) | 6 (15.8%) | |
BMI (kg/m2) | 24.7 ± 4.7 (17.3–36.9; 23.5–25.9) | 24.3 ± 5.1 (16.1–35.9; 22.6–26) | 0.402 |
Smoking | |||
Yes | 13 (20.3%) | 10 (26.3%) | 0.625 |
No | 51 (79.7%) | 28 (73.7%) | |
Side of pain | |||
Bilateral | 26 (68.4%) | 8 (47.1%) | 0.296 |
Right | 6 (15.8%) | 5 (29.4%) | |
Left | 6 (15.8%) | 4 (23.5%) | |
Temperature | 37.3 ± 0.5 (36–38.8; 37.1–37.4) | 37.1 ± 0.4 (36.5–38.6; 37–37.3) | 0.083 |
UOP status at presentation | |||
Normal | 37 (57.8%) | 28 (73.7%) | 0.162 |
Low | 27 (42.2%) | 10 (26.3%) | |
Loin tenderness | |||
Unilateral | 4 (30.8%) | 3 (75%) | 0.25 |
Bilateral | 9 (69.2%) | 1 (25%) | |
Pre-drainage dialysis | |||
Once | 9 (60%) | 3 (50%) | > 0.999 |
More than once | 6 (40%) | 3 (50%) | |
Mean parenchymal thickness (mm) | 13 ± 1.9 (8–16; 12.5–13.5) | 12.4 ± 2 (9.5–16; 11.7–13) | 0.075 |
Pathological type of malignancy | |||
Bladder cancer | 32 (50%) | 23 (60.5%) | 0.012 |
Prostate cancer | 3 (4.7%) | 7 (18.4%) | |
Colorectal cancer | 18 (28.1%) | 2 (5.3%) | |
Cervical cancer | 9 (14.1%) | 5 (13.2%) | |
Lymphoma | 2 (3.1%) | 1 (2.6%) | |
Type of malignancy relative to urinary tract | |||
Urinary | 35 (54.7%) | 30 (79%) | 0.024 |
Extraurinary | 29 (45.3%) | 8 (21%) | |
Random blood sugar | 128.8 ± 54.7 (72–330; 115.1–142.4) | 120.9 ± 54.9 (45–315; 102.8–138.9) | 0.151 |
Blood PH | 7.4 ± 0.1 (7.2–7.5; 7.3–7.4) | 7.38 ± 0.05 (7.3–7.5; 7.4–7.4) | 0.673 |
PCO2 (mmHg) | 24.4 ± 5.4 (14–36; 23.1–25.8) | 24.9 ± 6.1 (15–36; 22.9–26.9) | 0.832 |
HCO3 (mmol/L) | 15.2 ± 4.2 (6.7–23; 14.1–16.2) | 16.7 ± 4 (11.2–23; 15.4–18) | 0.128 |
Acid–base deficit (mmol/L) | − 9 ± 5.5 {− 21 to 1; − 10.34–(− 7.6)} | − 7.3 ± 5.5 (− 15 to 1; − 9.1 to 5.5) | 0.316 |
Laterality of drainage | |||
Unilateral | 30 (46.9%) | 20 (52.6%) | 0.721 |
Bilateral | 34 (53.1%) | 18 (47.4%) | |
SCr at presentation (mg/dl) | 7.5 ± 3.4 (2–17; 6.6–8.3) | 4.3 ± 1 (2.2–6.4; 4–4.7) | < 0.001 |
Post-drainage SCr measures (mg/dl) | |||
SCr at 1st day | 6.1 ± 3.1 (1.3–14.8; 5.3–6.8) | 3.9 ± 1.1 (1.9–6.2; 3.6–4.3) | < 0.001 |
SCr at 3rd day | 4.8 ± 3.2 (0.8–13; 4–5.6) | 3.5 ± 1.1 (1.4–5.7; 3.2–3.9) | 0.157 |
SCr at 5th day | 3.5 ± 2.6 (0.6–9.1; 2.8–4.1) | 3.2 ± 1 (1.5–5.3; 2.8–3.5) | 0.685 |
SCr at 7th day | 2.7 ± 2.3 (0.5–10.6; 2.1–3.2) | 2.7 ± 1 (1–5.6; 2.4–3.1) | 0.28 |
SCr at 10th day | 2.1 ± 1.5 (0.3–5.2; 1.7–2.4) | 2.4 ± 0.8 (1.2–3.9; 2.1–2.6) | 0.122 |
SCr at 15th day | 1.3 ± 0.75 (0.4–3.5; 1.1–1.5) | 1.6 ± 0.55 (0.8–3.9; 1.4–1.7) | 0.010 |
SCr at 21st day | 1.2 ± 0.62 (0.4–2.5; 1–1.3) | 1.5 ± 0.43 (0.8–2.5; 1.4–1.6) | 0.001 |
Time-to-nadir SCr (days) | 11 ± 5.8 (3–21; 9.5–12.4) | 15.4 ± 2.3 (7–21; 14.7–16.2) | < 0.001 |
SCr normalization rate during 21 days | |||
Normal SCr | 42 (65.6%) | 16 (42.1%) | 0.035 |
High SCr | 22 (34.4%) | 22 (57.9%) | |
Pyuria at 1 week after drainage | 28.5 ± 28.6 (5–100; 21.4–35.7) | 30.61 ± 29.9 (3–100; 20.8–40.5) | 0.934 |
Pus cells in urine after drainage /HPF | 28.5 ± 28.6 (5–100; 21.4–35.7) | 30.6 ± 29.9 (3–100; 20.8–40.5) | 0.934 |
SCr-Trs (mg/dL/day) | |||
SCr-Tr during 1st 3 days | 0.9 ± 0.7 (− 1–3.3; 0.7–1.1) | 0.3 ± 0.2 (0–0.7; 0.2–0.3) | < 0.001 |
Mode of SCr-Tr during 1st 3 days at 0.3 mg/dL/day value | |||
Rapid SCr-Tr (≥ 0.3 mg/dL/day) | 54 (84.4%) | 15 (39.5%) | < 0.001 |
Slow SCr-Tr (< 0.3 mg/dL/day) | 10 (15.6%) | 23 (60.5%) | |
Mode of SCr-Tr during 1st 3 days at 0.5 mg/dL/day value | |||
Rapid SCr-Tr (≥ 0.5 mg/dL/day) | 48 (75%) | 4 (10.5%) | < 0.001 |
Slow SCr-Tr (< 0.5 mg/dL/day) | 16 (25%) | 34 (89.5%) | |
Mode of SCr-Tr during 1st 3 days at 0.7 mg/dL/day value | |||
Rapid SCr-Tr (≥ 0.7 mg/dL/day) | 37 (57.81%) | 0 (0.0%) | < 0.001 |
Slow SCr-Tr (< 0.7 mg/dL/day) | 27 (42.2%) | 38 (100%) | |
Mode of SCr-Tr during 1st 3 days at 1 mg/dL/day | |||
Rapid SCr-Tr (≥ 1 mg/dL/day) | 22 (34.4%) | 0 (0%) | < 0.001 |
Slow SCr-Tr (< 1 mg/dL/day) | 42 (65.6%) | 38 (100%) | |
SCr-Tr during 1st week | 0.68 ± 0.39 (− 0.53 to 1.7; 0.58–0.78) | 0.23 ± 0.15 (− 0.19 to 0.57; 0.18–0.28) | < 0.001 |
Mean SCr-Tr during time-to-nadir SCr | 0.68 ± 0.42 (0.3–2.34; 0.57–0.78) | 0.18 ± 0.067 (0.03–0.29; 0.16–0.21) | < 0.001 |
Mode of SCr-Tr during time-to-nadir SCr at 0.1 mg/dL/day value | |||
Rapid SCr-Tr (≥ 0.1 mg/dL/day) | 64 (100%) | 35 (92.1%) | 0.049 |
Slow SCr-Tr (< 0.1 mg/dL/day) | 0 (0%) | 3 (7.9%) | |
Mode of SCr-Tr during time-to-nadir at 0.5 mg/dL/day value | |||
Rapid SCr-Tr (≥ 0.5 mg/dL/day) | 38 (59.4%) | 0 (0%) | < 0.001 |
Slow SCr-Tr (< 0.5 mg/dL/day) | 26 (40.6%) | 38 (100%) | |
SCr-Tr during 1st 3 days-SCr-Tr during 1st week (mg/dL/day) | 0.21 ± 0.5 (− 1.33 to 1.7; 0.09–0.33) | 0.05 ± 0.13 (− 0.2 to 0.36; 0.004–0.09) | 0.079 |
SCr-Tr during 1st 3 days–SCr-Tr during time-to-nadir SCr (mg/dL/day) | 0.2 ± 0.5 (− 1.28 to 1.56; [0.09–0.34) | 0.09 ± 0.15 (− 0.17 to 0.51; 0.04–0.14) | 0.478 |