Variables | Rapid SCr trajectory (≥ 0.5 mg/dL/day) (n = 52) | Slow SCr trajectory (< 0.5 mg/dL/day) (n = 50) | p value |
---|---|---|---|
Age (year) | 57.4 ± 15.1 (24–77; 53.2–61.6) | 61.9 ± 14.2 (23–86; 57.9–65.9) | 0.253 |
Gender | |||
Men | 37 (71.2%) | 36 (72%) | > 0.999 |
Women | 15 (28.8%) | 14 (28%) | |
BMI (kg/m2) | 24.6 ± 4.8 (17.3–36.9; 23.2–25.9) | 24.6 ± 4.9 (16.1–35.9; 23.2–26) | 0.820 |
Comorbidity | |||
Yes | 33 (63.5%) | 31 (62%) | 0.898 |
No | 19 (36.5%) | 19 (38%) | |
Smoking | |||
Yes | 13 (25%) | 10 (20%) | 0.714 |
No | 39 (75%) | 40 (80%) | |
Pain | |||
None | 23 (44.2%) | 24 (48%) | 0.181 |
Right | 5 (9.6%) | 6 (12%) | |
Left | 3 (5.8%) | 7 (14%) | |
Bilateral | 21 (40.4%) | 13 (26%) | |
Temperature | 37.3 ± 0.5 (36.5–38.8; 37.1–37.4) | 37.2 ± 0.5 (36–38.6; 37–37.3) | 0.213 |
UOP status at presentation | |||
Normal | 22 (57.89%) | 43 (67.19%) | 0.465 |
Low | 16 (42.11%) | 21 (32.81%) | |
Tenderness | |||
Unilateral | 4 (36.4%) | 3 (50%) | 0.644 |
Bilateral | 7 (63.6%) | 3 (50%) | |
Pre-drainage dialysis | |||
Once | 8 (50%) | 1 (20%) | 0.338 |
More than once | 8 (50%) | 4 (80%) | |
Uremic symptoms | |||
Yes | 16 (30.8%) | 13 (26%) | 0.263 |
No | 36 (69.2%) | 37 (74%) | |
Mean parenchymal thickness (mm) | 13.6 ± 1.6 (9–16; 13.1–14.1) | 12.3 ± 2 (8–16; 11.8–12.8) | < 0.001 |
Pathological type of malignancy | |||
Bladder cancer | 26 (50%) | 29 (58%) | 0.119 |
Prostate cancer | 3 (5.8%) | 7 (14%) | |
Colorectal cancer | 15 (28.9%) | 5 (10%) | |
Uterine cervical cancer | 6 (11.5%) | 8 (16%) | |
Lymphoma | 2 (3.8%) | 1 (2%) | |
Type of malignancy relative to urinary tract | |||
Urinary | 19 (50%) | 46 (71.9%) | 0.045 |
Extraurinary | 19 (50%) | 18 (28.1%) | |
Random blood sugar | 134.1 ± 62.3 (75–330; 116.8–151.4) | 117.3 ± 44.4 (45–280; 104.6–130) | 0.18 |
Blood PH | 7.36 ± 0.09 (7.15–7.47; 7.34–7.39) | 7.37 ± 0.05 (7.23–7.47; 7.367.39) | 0.96 |
PCO2 (mmHg) | 24.9 ± 5 (14–36; 23.5–26.3) | 24.3 ± 6.3 (15–36; 22.5–26.1) | 0.411 |
Acid–base deficit (mmol/L) | − 8.5 ± 5.8 {(− 21)− 1; (− 10.1)–(− 6.9)} | − 8.2 ± 5.3 {(− 20)–1; (− 9.7)–6.7} | 0.771 |
HCO3 (mmol/L) | 15.5 ± 4.3 (9–23; 14.3–16.7) | 16 ± 4 (6.7–23; 14.8–17.1) | 0.475 |
Laterality of drainage | |||
Unilateral | 24 (46.2%) | 26 (52%) | 0.695 |
Bilateral | 28 (53.8%) | 24 (48%) | |
SCr at presentation (mg/dL) | 7.8 ± 3.4 (2.6–17; 6.9–8.8) | 4.7 ± 1.8 (2–9.2; 4.2–5.2) | < 0.001 |
Post-drainage SCr measures (mg/dL) | |||
SCr at 1st day | 6.1 ± 3.2 (1.3–14.8; 5.2–7) | 4.4 ± 1.8 (1.7–9; 3.9–4.9) | 0.013 |
SCr at 3rd day | 4.6 ± 3.2 (0.8–13; 3.7–5.5) | 4.1 ± 1.9 (1.2–9.8; 3.5–4.6) | 0.997 |
SCr at 5th day | 3.2 ± 2.4 (0.6–8.2; 2.5–3.8) | 3.5 ± 1.8 (0.9–9.1; 3–4) | 0.112 |
SCr at 7th day | 2.4 ± 1.9 (0.5–6.5; 1.9–2.9) | 3 ± 1.8 (0.5–10.6; 2.5–3.5) | 0.044 |
SCr at 10th day | 1.9 ± 1.4 (0.3–5; 1.5–2.3) | 2.5 ± 1.2 (0.5–5.2; 2.1–2.8) | 0.021 |
SCr at 15th day | 1.2 ± 0.7 (0.4–2.9; 1–1.4) | 1.6 ± 0.68 (0.5–3.9; 1.4–1.7) | 0.007 |
SCr at 21st day | 1.1 ± 0.6 (0.4–2.5; 1–1.3) | 1.5 ± 0.5 (0.5–2.5; 1.3–1.6) | < 0.001 |
Time-to-nadir SCr (days) | 11.3 ± 6 (3–21; 9.7–13) | 14 ± 4 (5–21; 12.9–15.1) | 0.014 |
SCr normalization rate during 21 days | |||
Normal SCr | 37 (71.2%) | 21 (42%) | 0.006 |
High SCr | 15 (28.8%) | 29 (58%) | |
Pus cells in urine after drainage/ HPF | 24.9 ± 26.3 (6–100; 17.6–32.2) | 33.9 ± 31.1 (3–100; 25–42.7) | 0.169 |
SCr-Trs (mg/dL/day) | |||
Mean SCr-Tr during 1st 3 days | 1.1 ± 0.6 (0.5–3.3; 0.9–1.3) | 0.2 ± 0.2 {(− 1)–0.5; 0.2–0.3)} | < 0.001 |
Mode of SCr-Tr during 1st 3 days at 0.3 mg/dL/day value | |||
Rapid (≥ 0.3 mg/dL/day) | 52 (100%) | 17 (34%) | < 0.001 |
Slow (< 0.3 mg/dL/day) | 0 (0%) | 33 (66%) | |
Mode of SCr-Tr during 1st 3 days at 0.7 mg/dL/day value | |||
Rapid (≥ 0.7 mg/dL/day) | 37 (71.2%) | 0 (0%) | < 0.001 |
Slow (< 0.7 mg/dL/day) | 15 (28.8%) | 50 (100%) | |
Mode of SCr-Tr during 1st 3 days at 1 mg/dL/day value | |||
Rapid (≥ 1 mg/dL/day) | 22 (42.3%) | 0 (0%) | < 0.001 |
Slow (< 1 mg/dL/day) | 30 (57.7%) | 50 (100%) | |
SCr-Tr during 1st week | 0.8 ± 0.4 (0.2–1.7; 0.7–0.9) | 0.2 ± 0.2 (− 0.5 to 0.8; 0.2–0.3) | < 0.001 |
Mean SCr-Tr during time-to-nadir SCr | 0.7 ± 0.4 (0.2–2.3; 0.6–0.9) | 0.2 ± 0.1 (0–0.8; 0.2–0.3) | < 0.001 |
Mode of SCr-Tr during time-to-nadir SCr at 0.1 mg/dL/day value | |||
Rapid (≥ 0.1 mg/dL/day) | 52 (100%) | 47 (94%) | 0.114 |
Slow (< 0.1 mg/dL/day) | 0 (0%) | 3 (6%) | |
Mode of SCr-Tr during time-to-nadir at 0.3 mg/dl/day value | |||
Rapid (≥ 0.3 mg/dL/day) | 48 (92.31%) | 16 (32.0%) | < 0.001 |
Slow (< 0.3 mg/dL/day) | 4 (7.69%) | 34 (68.0%) | |
Mode of SCr-Tr during time-to-nadir SCr at 0.5 mg/dl/day value | |||
Rapid (≥ 0.5 mg/dL/day) | 37 (71.15%) | 1 (2.0%) | < 0.001 |
Slow (< 0.5 mg/dL/day) | 15 (28.85%) | 49 (98.0%) | |
SCr-Tr during 1st 3 days-SCr-Tr during 1st week (mg/dL/day) | 0.3 ± 0.5 (− 0.37 to 1.7; 0.2–0.5) | − 0.03 ± 0.2 (− 1.3 to 0.2; − 0.1 to 0.04) | < 0.001 |
SCr-Tr during 1st 3 days–SCr-Tr during time-to-nadir (mg/dL/day) | 0.4 ± 0.5 (− 0.3 to 1.6; 0.2–0.5) | − 0.04 ± 0.3 (− 1.3 to 0.3; − 0.1 to 0.04) | < 0.001 |