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Table 2 Risk factors for cancer-specific death of patients with de novo UTUC

From: De novo upper tract urothelial carcinoma after renal transplantation: a single-center experience in China

Variable

Univariate analysis

Multivariate analysis

HR (95% CI)

p-value

HR (95% CI)

p-value

Gender

    

Male

1 (Ref.)

   

Female

0.937 (0.327–2.690)

0.904

  

Age

    

 ≤ 65y

1 (Ref.)

   

 > 65y

1.255 (0.481–3.276)

0.643

  

AA exposure

    

No

1 (Ref.)

   

Yes

1.231 (0.471–3.214)

0.671

  

Tumor staging

    

 < T2

1 (Ref.)

 

1 (Ref.)

 

 ≥ T2

4.488 (1.996–10.093)

 < 0.001

3.234 (1.342–7.795)

0.009

Lymph node staging

    

N0

1 (Ref.)

 

1 (Ref.)

 

N + 

23.486 (7.815–70.585)

 < 0.001

12.91 (4.217–39.51)

 < 0.001

Tumor grade

    

G1/G2

1 (Ref.)

 

1 (Ref.)

 

G3

2.635 (1.264–5.493)

0.01

1.416 (0.607–3.301)

0.421

Multifocality

    

No

1 (Ref.)

   

Yes

1.518 (0.678–3.397)

0.31

  

Concomitant BC

    

No

1 (Ref.)

   

Yes

1.878 (0.918–3.842)

0.084

  
  1. AA Aristolochic acid, BC Bladder cancer, CI Confidence interval, HR Hazard ratio, Ref. Reference
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