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Table 3 Risk factors for contralateral recurrence of patients with de novo UTUC

From: De novo upper tract urothelial carcinoma after renal transplantation: a single-center experience in China

Variable

Univariate analysis

Multivariate analysis

HR (95% CI)

p-value

HR (95% CI)

p-value

Gender

    

Male

1 (Ref.)

   

Female

0.519 (0.158–1.703)

0.279

  

Age

    

 ≤ 65y

1 (Ref.)

   

 > 65y

0.910 (0.462–1.792)

0.785

  

AA exposure

    

No

1 (Ref.)

 

1 (Ref.)

 

Yes

4.817 (1.154–20.16)

0.031

4.714 (1.096–20.272)

0.037

Tumor staging

    

 < T2

1 (Ref.)

   

 ≥ T2

1.724 (0.801–3.710)

0.163

  

Lymph node staging

    

N0

1 (Ref.)

   

N + 

0.047 (0.000–8582.93)

0.621

  

Tumor grade

    

G1/G2

1 (Ref.)

   

G3

0.796 (0.376–1.687)

0.552

  

Multifocality

    

No

1 (Ref.)

 

1 (Ref.)

 

Yes

2.212 (1.033–4.737)

0.041

1.196 (0.438–3.271)

0.727

Concomitant BC

    

No

1 (Ref.)

   

Yes

1.786 (0.874–3.651)

0.112

  

Tumor location

    

Renal pelvis only

1 (Ref.)

 

1 (Ref.)

 

Ureter only

1.676 (0.533–5.273)

0.377

2.132 (0.665–6.836)

0.203

Pelvis and ureter

3.114 (1.052–9.215)

0.040

2.861 (0.787–10.396)

0.110

  1. AA Aristolochic acid, BC Bladder cancer, CI Confidence interval, HR Hazard ratio, Ref. Reference