Fig. 2From: A phase II randomized trial of metastasis-directed therapy with alpha emitter radium-223 in men with oligometastatic castration-resistant prostate cancer (MEDAL)Intervention and assessment schedule for the MEDAL trial according to the Recommendations for Interventional Trials (SPIRIT). Patients will visit the hospital every 4Â weeks until about 24Â weeks after radiotherapy, and then every 3Â months for the next 2Â years to collect data. *according to the Common Toxicity Criteria for Adverse Events (CTCAE v 5.0), **questionnaires: FACT-P, EQ-5D. PSA Prostate-specific antigen, QOL Quality of lifeBack to article page