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Table 3 Correlation analysis between SERPINE1 and biomarkers of immune cells in ccRCC determined by GEPIA database

From: SERPINE1 and its co-expressed genes are associated with the progression of clear cell renal cell carcinoma

Immune cell

Biomarker

Spearman's Correlation

p-value

B cell

CD19

0.259592948

1.13E-09

 

CD79A

0.224938142

1.49E-07

CD8 + T cell

CD8A

0.110395509

0.010683103

 

CD8B

0.07150304

0.098827444

CD4 + T cell

CD4

0.247484445

6.79E-09

M1 macrophage

NOS2

0.038746875

0.371526712

 

IRF5

 − 0.100882922

0.019714615

 

PTGS2

0.335569557

1.61E-15

M2 macrophage

CD163

0.446177803

1.74E-27

 

VSIG4

0.294943278

3.53E-12

 

MS4A4A

0.347265227

1.40E-16

Neutrophil

CEACAM8

 − 0.022888648

0.597672419

 

ITGAM

0.116464119

0.007056392

 

CCR7

0.309636063

2.50E-13

Dendritic cell

HLA-DPB1

0.091357962

0.034805998

 

HLA-DQB1

0.053522596

0.216900999

 

HLA-DRA

0.108000281

0.012518625

 

HLA-DPA1

0.08194073

0.05845524

 

CD1C

0.01007617

0.816301262

 

NRP1

0.256830988

1.72E-09

 

ITGAX

0.145059254

0.000773698

Monocyte

CSF1R

0.180369596

2.7562E-05

 

CD86

0.213463917

6.40E-07

Treg

FOXP3

0.302728148

8.83E-13

 

CCR8

0.222884005

1.95E-07

 

TGFB1

0.478831915

5.89E-32