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Table 4 Pooled outcomes at 1, 3, 6, and 12 months postoperatively and complication incidence rates

From: Efficacy and safety of Water Vapor Thermal Therapy in the treatment of benign prostate hyperplasia: a systematic review and single-arm Meta-analysis

Outcomes

NO. of patients

Pooled effect

95%CI

P

I2

Exclude

IPSS 1mo

635

-6.77

(-8.24, -5.30)

< 0.001

77.50%

 

IPSS 3mos

502

-11.26

(-12.52, -9.99)

< 0.001

63.40%

 

IPSS 6mos

461

-12.20

(-13.00, -11.41)

< 0.001

19.80%

 

IPSS 12mos

480

-11.37

(-12.53, -10.21)

< 0.001

58.90%

 

Qol 1mo

612

-1.41

(-1.80, -1.03)

< 0.001

83.60%

 

Qol 3mos

489

-2.35

(-2.65, -2.04)

< 0.001

67.90%

 

Pre-Qol 6mos

448

-2.61

(-2.96, -2.25)

< 0.001

74.6%

 

Qol 6mos

407

-2.45

(-2.62, -2.27)

< 0.001

35.60%

[11]

Qol 12mos

466

-2.59

(-2.92, -2.26)

< 0.001

76.80%

 

Qmax 1mo

344

2.74

(1.83, 3.66)

< 0.001

56.90%

 

Pre-Qmax 3mos

314

4.54

(2.6, 6.47)

< 0.001

89.60%

[8]

Qmax 3mos

312

5.28

(4.54, 6.01)

< 0.001

44.30%

 

Qmax 6mos

280

5.15

(4.45, 5.85)

< 0.001

0

 

Qmax 12mos

251

5.26

(4.53, 5.99)

< 0.001

28.70%

 

PVR 3mos

231

-12.42

(-19.88, -4.96)

< 0.001

28.60%

[2, 4, 11]

PVR 6mos

212

-9.48

(-19.72, 0.75)

0.137

20.10%

PVR 12mos

203

-13.18

(-24.32, -2.03)

< 0.001

18.70%

BPH II 3mos

293

-3.74

(-4.60, -2.89)

< 0.001

76.80%

 

BPH II 6mos

263

-4.45

(-4.83, -4.07)

< 0.001

48.20%

 

BPH II 12mos

225

-4.45

(-5.10, -3.80)

< 0.001

58.50%

 

Pre-IIEF-EF 6mos

179

-0.05

(-1.17, 1.67)

0.953

74.50%

 

IIEF-EF 6mos

175

0.37

(-0.71, 1.45)

0.439

15.90%

[8]

IIEF-EF 12mos

159

0.16

(-0.91, 1.24)

0.768

0

 

MSHQ-EjD 1mo

90

0.31

(-0.53, 1.16)

0.936

34.10%

 

MSHQ-EjD 3mos

189

0.34

(-0.26, 0.94)

0.264

0

 

Pre-MSHQ-EjD 6mos

161

0.89

(-0.51, 2.29)

0.213

70.80%

 

MSHQ-EjD 6mos

149

0.09

(-0.55, 0.74)

0.699

49.30%

[11]

MSHQ-EjD 12mos

146

-0.03

(-0.50, 0.96)

0.728

49.30%

 

MSHQ-bother 1mo

90

-0.35

(-0.67, -0.03)

0.076

26%

 

MSHQ-bother 3mos

189

-0.36

(-0.62, -0.11)

0.027

45.10%

 

MSHQ-bother 6mos

161

-0.66

(-1.23, -0.10)

0.022

66.40%

 

MSHQ-bother 12mos

147

-0.75

(-1.26, -0.25)

0.004

51.60%

 

Adverse events

      

Pre-Hematuria

582

22%

(8%, 42%)

< 0.01

96.41%

 

Hematuria

339

14%

(10%, 18%)

< 0.01

0

[6, 8]

Dysuria

112

21%

(14%, 29%)

< 0.01

77.38%

 

Hematospermia

42

10%

(2%, 22%)

< 0.01

89.47%

 

UTI

544

7%

(3%, 11%)

< 0.01

68.38%

 

Urinary retention

741

12%

(6%, 19%)

< 0.01

86.07%

 

Urinary urgency

414

10%

(5%, 17%)

< 0.01

73.28%

 

Urinary frequency

338

10%

(3%, 20%)

< 0.01

85.78%

 

Pelvic pain

335

3%

(1%, 6%)

< 0.01

0

 

Retreatment

764

3%

(2%, 5%)

< 0.01

0

 
  1. Abbreviations: mos: months; IPSS: International Prostate Symptom Score; Qol: IPSS quality of life scale; PVR: postvoid residual; Qmax: maximum urine flow rate; BPH II: Benign Prostate Hypertrophy Impact Index; IIEF-EF: International Index of Erectile Function erectile function domain; MSHQ-EjD: Male Sexual Health Questionnaire for Ejaculatory Dysfunction; UTI: urinary tract infection; CI: confidence intervals