Table 3 Univariate and multivariate cox regression analysis for progression-free survival
From: Serum lactate dehydrogenase level predicts the prognosis in bladder cancer patients
Factors | Progression-free survival | |||
|---|---|---|---|---|
Univariate | Multivariate | |||
HR (95%CI) | P value | HR (95%CI) | P value | |
Age | ||||
≥ 64 vs. < 64 years | 1.03 (0.66–1.60) | 0.910 | – | – |
Sex | ||||
Male vs. female | 1.52 (0.84–2.76) | 0.165 | – | – |
Smoking | ||||
Yes vs. no | 1.59 (1.02–2.48) | 0.041 | 1.46 (0.92–2.32) | 0.110 |
Pathological type | ||||
Squamous cell carcinoma/adenocarcinoma vs. transitional cell carcinoma | 9.12 (4.76–17.49) | < 0.001 | 3.07 (1.37–6.88) | 0.007 |
T stage | ||||
T2–3 vs. Ta, Tis, T1 | 2.69 (1.72–4.22) | < 0.001 | 1.66 (0.98–2.81) | 0.061 |
N stage | ||||
N1–3 vs. N0 | 13.67 (7.58–24.65) | < 0.001 | 3.12 (0.84–11.60) | 0.090 |
M stage | ||||
M1 vs. M0 | 18.37 (9.42–35.84) | < 0.001 | 3.02 (0.89–10.28) | 0.077 |
Tumor size | ||||
≥ 3 vs. < 3 cm | 3.20 (1.60–6.42) | 0.001 | 2.81 (1.37–5.78) | 0.005 |
LVI | ||||
Present vs. absent | 1.82 (1.17–2.83) | 0.008 | 0.86 (0.47–1.55) | 0.604 |
PNI | ||||
Present vs. absent | 2.18 (1.22–3.91) | 0.008 | 1.07 (0.49–2.35) | 0.870 |
Multifocality | ||||
Multifocal vs. unifocal | 1.01 (0.60–1.71) | 0.978 | – | – |
LDH | ||||
High vs. low | 3.08 (1.96–4.83) | < 0.001 | 1.70 (1.00–2.87) | 0.049 |