Fig. 7

Construction and validation of metabolism-associated prognostic signature for prostate cancer. A Forest plot of the DFS-related MAGs based on univariate cox analysis. B LASSO coefficient profiles of the selected MAGs at optimal λ (grey line) for metabolism-related clustering. C LASSO regression model with 10-cross validation was used to select the optimal λ (dash line) with minimum mean square error (red dots). D–F The high-risk and low-risk groups are based on the median value of risk score (up), the survival status between high-risk and low-risk groups (middle), and the gene expression (bottom), in TCGA-PARD, GSE70768, and GSE70769 cohorts. G–I KM DFS curves of high-risk and low-risk groups in TCGA-PARD, GSE70768, and GSE70769 cohorts. J–L ROC curves for 1-, 3-, and 5-year of DFS in TCGA-PARD, GSE70768, and GSE70769 cohorts