Fig. 4

MiR-183-5p facilitated the migration and invasion of PCa cells through down-regulation TET1. (A) The expression level of TET1 in the co-transfected PCa cell lines of miR-183-5p and TET1 was detected by qRT-PCR. (B) The migration(vertical) in the two co-transfected PCa cell lines of miR-183-5p and TET1 was measured using a transwell assay (magnification: 10×). (C) The crawling ability in the two co-transfected PCa cell lines of miR-183-5p and TET1 was measured using a wound healing assay (magnification: 10×). (D) The invasion in the two co-transfected PCa cell lines of miR-183-5p and TET1 was measured with transwell assay (magnification: 10×). Data are presented as mean ± SEM; ^***P < 0.001; ^**P < 0.01; ^*P < 0.05