Fig. 3

Inhibition of miR-105-5p reversed the carcinogenic effects of CSCs-exo. A The expression levels of miR-105-5p in CSCs, T24 and EJ cells were measured by RT-qPCR. B The expression levels of miR-105-5p were measured in EJ and T24 cells after incubated with CSCs-exo. C miR-105-5p inhibitor was transfected into CSCs, and CSCs-exo. D Cell viability, E and F migration and G invasion of EJ and T24 cells were determined after incubation with CSCs-exo. Experiments were conducted thrice for each approach. ^*P < 0.05; ^**P < 0.01; ^***P < 0.001; ^****P < 0.0001. CSCs Cancer stem cells, CSCs-exo Exosomes derived from cancer stem cells