Table 1 Detailed information on the data used in Mendelian randomization analysis
Traits | Data sources | Sample size(cases/controls) | Population | Use |
|---|---|---|---|---|
IBD | de Lange et al. [24] | 59,957(25,042/34,915) | European | Exposure/Outcome |
CD | 40,266(12,194/28,072) | |||
UC | 45,975(12,366/33,609) | |||
IBD (val) | Liu et al. [25] | 34,652(12,882/21,770) | European | Exposure for validation |
CD (val) | 20,883(5956/14,927) | |||
UC (val) | 27,432(6968/20,464) | |||
KSD | FinnGen | 218,414(4969/213,445) | European | Outcome/Exposure |
HDL-C | UK Biobank [34] | 403,943 | European | Confounders for MVMR analyses |
LDL-C | 440,546 | |||
TG | 441,016 | |||
BMI | Hoffmann et al. [33] | 315,347 | European | Confounder for MVMR analysis |