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Table 4 Results of meta-analysis comparing mPCNL and RIRS

From: Efficacy and safety of minimally invasive percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of upper urinary tract stones (> 1 cm): a systematic review and meta-analysis of 18 randomized controlled trials

Outcomes

No.of studies

SamPle size

Heterogeneity(Total)

W(S)MD/RR(95%CI)

P value(Total)

  

mPCNL

RIRS

chi2

df

I2%

P value

  

Overall SFR

17

862

821

42.3

16

62.1

0.01

1.08(1.03–1.14)

P = 0.002

SFR(stone 1–2 cm)

11

571

573

28.34

10

64.7

0.002

1.09(1.03–1.15)

P = 0.003

SFR(stone 2–3 cm)

3

123

122

4.78

2

58.2

0.092

1.19(1.05–1.36)

P = 0.007

Operation time

18

887

846

836.6

17

98.00%

0

-6.82(-15.45, 1.81)

P = 0.122

Operation time(2013–2019)

8

341

353

322.5

7

97.80%

0

-0.65(-16.56, 15.26)

p = 0.936

Operation time(2019–2022)

10

546

493

62.9

9

85.70%

0

-10.85(-16.76,-4.94)

p<0.001

Transfusion

9

419

420

0.78

6

0

0.993

5.04(1.62–15.65)

P = 0.005

Hospitalization time

17

827

786

810.5

16

98

0

1.01(0.53,1.5)

P<0.001

Pain visual analogue score

7

378

388

81.65

6

92.7

0

0.75(0.04–1.46)

P = 0.037

Hb drop

11

723

667

56.4

10

82.3

0

0.27(0.14–0.41)

P<0.001

Complication ratio

16

832

792

38.29

15

60.8

0.001

1.17(0.82–1.68)

P = 0.39

Clavien-Dindo(I-II)

17

857

817

40.47

16

60.5

0.001

1.03(0.74–1.42)

P = 0.88

Clavien-Dindo(III)

12

583

542

8.25

7

15.2

0.311

1.89(1.014–3.53)

P = 0.045

Cost

4

221

183

5.18

3

42

0.159

-0.97(-1.19, -0.76)

P<0.001

  1. CI Confidence interval, WMD Weighted mean difference, SMD Standardized mean difference, mPCNL Minimally invasive percutaneous nephrolithotomy, RIRS Retrograde intrarenal surgery, RR Risk ratio, SFR Stone free rate;