Effect of the TERT mutation on the prognosis of patients with urothelial carcinoma: a systematic review and meta-analysis

Table 2 The variables of the included studies

Stusy	Survival outcomes	2-yr		5-yr		HR	LCI	UCI	Data source	NOS score
Stusy	Survival outcomes	Mutation	Wild	Mutation	Wild	HR	LCI	UCI	Data source	NOS score
Rachakonda 2013	OS	0.80	0.81	0.68	0.73	1.34	0.81	2.23	Published	9
Nakanishi 1999	OS	0.66	0.85	0.57	0.79	2.50	1.26	4.96	Estimated^a	8
Nakanishi 1999	RFS	0.50	0.70	0.39	0.65	1.94	1.14	3.31	Estimated^a	8
Yang CH 2008	RFS	0.81	0.91	0.71	0.84	NA	NA	NA	Estimated	7
Sumit 2017	OS	0.69	0.79	0.57	0.68	2.31	1.46	3.65	Published	8
	DSS	0.69	0.79	0.58	0.69	2.23	1.41	3.53
	MFS	0.62	0.68	0.52	0.58	1.63	1.05	2.53
Song Wu 2013	OS	0.84	0.98	0.66	0.98	7.61	1.69	34.19	Estimated	8
Ismail 2015	OS	0.68	0.77	0.49	0.68	1.35	0.80	2.29	Published	9
Jenny 2019	OS	0.68	0.67	0.40	0.67	0.35	0.11	1.12	Estimated	8
	RFS	0.54	0.22	0.36	0.22	0.41	0.21	0.77
	DSS	0.91	1	0.87	1	NA	NA	NA
Ivan 2021	OS	0.45	0.24	0.32	0.24	0.3	0.1	0.93	Published	8
Neal 2023	OS	0.32	0.31	0.25	0.07	0.91	0.59	1.40	Published	8

HR Hazard ratio, LCI Low confidence interval, UCI Up confidence interval, NOS The Newcastle–Ottawa Scale, NA Not applicable, ^aSurvival data estimated from Kaplan—Meier curves using published methodology

ISSN: 1471-2490