Table 1 Demographic data of all prostate cancer patient who underwent laparoscopic radical prostatectomy included in the analysis for primary cohort and validation cohort
From: Prediction of biochemical recurrence after laparoscopic radical prostatectomy
Variables | All | Primary cohort | Validation | p-value |
|---|---|---|---|---|
Total | 370 | 235 | 135 | |
Age (yrs) | 0.422 | |||
Mean (IQR) | 67.7 (63–72) | 68.4 (64–73) | 67 (62–72) | |
BMI (Kg/m2) | 0.365 | |||
Median (IQR) | 24.3 (22.3,26.4) | 24.4 (22.6,26.2) | 24.2 (21.2,26.4) | |
Unknown | 7 | 5 | 2 | |
Blood loss (mL) | 0.542 | |||
Median (IQR) | 520 (280,820) | 500 (300,800) | 540 (280,820) | |
Prostate size | 0.416 | |||
Median (IQR) | 46 (32.52) | 42 (33.5,53.5) | 50 (32,56) | |
Unknown | 6 | 4 | 2 | |
PSA group (ng/mL) | 0.128 | |||
<= 20 | 254 (68.6) | 153 (75.1) | 101 (74.8) | |
>20 | 116 (31.4) | 82 (34.9) | 34 (25.2) | |
Pre operative MRI (PIRSADs) | 0.419 | |||
2 | 5 (1.4) | 4 (1.7) | 1 (0.7) | |
3 | 13 (3.5) | 9 (3.8) | 4 (3.0) | |
4 | 137 (37) | 87 (37.0) | 50 (37.0) | |
5 | 215 (58.1) | 135 (57.5) | 80 (59.3) | |
PSA preoperative | 0.6 | |||
Median (IQR) | 13.5 (9.0,24.8) | 13.6 (9.3,24.8) | 13.5 (9.0,25.0) | |
Gleason | 0.365 | |||
6 | 81 (21.9) | 61 (26) | 20 (14.8) | |
7 | 217 (58.7) | 127 (54) | 90 (66.7) | |
8 | 30 (8.1) | 20 (8.5) | 10 (7.4) | |
9 | 36 (9.7) | 26 (11.1) | 10 (7.4) | |
10 | 6 (1.6) | 1 (0.4) | 5 (3.7) | |
Gleason group | 0.225 | |||
6 | 91 (25.6) | 61 (26) | 30 (22.2) | |
7 | 197 (53.2) | 127 (54) | 70 (51.9) | |
>=8 | 82 (22.2) | 47 (20) | 35 (25.9) | |
Grade group | 0.437 | |||
1 | 109 (29.4) | 61 (26) | 48 (35.6) | |
2 | 128 (34.6) | 78 (33.2) | 50 (37.0) | |
3 | 67 (18.2) | 49 (20.9) | 18 (13.3) | |
4 | 29 (7.8) | 20 (8.5) | 9 (6.7) | |
5 | 37 (10) | 27 (11.5) | 10 (7.4) | |
Margin | 0.286 | |||
Negative | 233 (63.0) | 161 (68.5) | 72 (53.3) | |
Positive | 137 (37.0) | 74 (31.5) | 63 (46.7) | |
LVI | 0.263 | |||
Negative | 285 (77.0) | 180 (76.6) | 105 (77.7) | |
Positive | 85 (22.3) | 55 (23.4) | 30 (22.3) | |
Total lymph node | 0.492 | |||
Median (IQR) | 4 (2,7) | 4 (2,6) | 4 (2,7) | |
T | 0.476 | |||
1 | 103 (27.8) | 63 (26.8) | 40 (29.6) | |
2 | 180 (48.6) | 115 (48.9) | 65 (48.1) | |
3a | 37 (10) | 23 (9.8) | 14 (10.3) | |
3b | 50 (13.5) | 34 (14.5) | 16 (11.8) | |
BCR rate | 165 (44.6) | 105 (44.7) | 60 (44.4) | 0.324 |
Time to BCR | 0.422 | |||
Median (IQR) | 17.6 (3.6,41.2) | 18.1 (3.8,41.1) | 17.2 (3.6,40.0) |