Table 2 Predictive factors - Univariable analysis and multivariable analysis

HR

95% Cl

P value

HR

95% Cl

P value

Initial PSA (ng/mL)

 <=20

Ref

Ref

 > 20

4.4

2.6–7.7

< 0.001

3.2

1.8–5.8

< 0.001

Gleason score

 6

Ref

 7

2.7

1.5–5.1

0.002

2.2

1.2–3.3

< 0.001

 ≥ 8

8.4

4.3–16.3

< 0.001

5.4

2.6–6.8

< 0.001

Gleason grade group

 1

Ref

 2

2.2

1.1–4.2

0.025

1.5

0.7–2.9

0.29

 >=3

5.1

2.8–9.6

< 0.001

2.2

1.1–4.4

0.022

Margin status

 Negative

Ref

Ref

 Positive

2.6

1.8–3.9

< 0.001

1.5

1.0-2.3

0.046

LVI status

 Negative

Ref

Ref

 Positive

2.7

1.8–4.1

< 0.001

1.0

0.6–1.6

0.841

pT stage

 2

Ref

Ref

 3a

3.2

1.9–5.4

< 0.001

2.8

1.6–4.8

< 0.001

 3b

8.4

5.3–13.3

< 0.001

5.2

3.1–8.6

< 0.001

pN stage

 0

Ref

Ref

0.028

 1

4.8

2.6–9.1

< 0.001

3.1

1.7–5.8