Neutrophil-to-lymphocyte ratio as a promising non-invasive biomarker for symptom assessment and diagnosis of interstitial cystitis/bladder pain syndrome

Table 1 Baseline characteristics for each group

Characteristic	Normal	IC/BPS	OAB	P value	IC/BPS vs. Normal	Normal vs. OAB	IC/BPS vs. OAB
n	150	70	20
HP, n (%)				0.311	1.000	0.218	0.265
0	107 (44.6%)	50 (20.8%)	11 (4.6%)
1	43 (17.9%)	20 (8.3%)	9 (3.8%)
DM, n (%)				0.333	0.809	0.235	0.454
0	136 (56.7%)	62 (25.8%)	16 (6.7%)
1	14 (5.8%)	8 (3.3%)	4 (1.7%)
Proteinuria, n (%)				0.071	0.594	0.068	0.213
0	148 (61.7%)	68 (28.3%)	18 (7.5%)
1	2 (0.8%)	2 (0.8%)	2 (0.8%)
NLR	1.64 ± 0.5	2.59 ± 1.28	1.77 ± 0.47	< 0.001	< 0.001	0.247	< 0.001
Age, year	43.28 ± 6.92	51.23 ± 16.72	64.4 ± 10.76	< 0.001	< 0.001	< 0.001	< 0.001
Height, cm	162.07 ± 4.51	161.04 ± 6.15	158.7 ± 6.4	0.018	0.163	0.003	0.140
Weight, Kg	57.65 ± 7.97	61.71 ± 10.22	62.48 ± 12.74	0.010	0.004	0.114	0.782
BMI	21.95 ± 2.92	23.8 ± 3.78	24.65 ± 3.9	< 0.001	< 0.001	0.007	0.381
WBC, 109/L	5.62 ± 1.32	6.03 ± 1.72	5.75 ± 1.83	0.175	0.057	0.702	0.531
LYMPH#, 109/L	2.13 ± 1.73	1.61 ± 0.55	1.79 ± 0.49	0.037	0.016	0.387	0.197
NEUT#, 109/L	3.17 ± 0.95	3.74 ± 1.26	3.12 ± 1.08	< 0.001	< 0.001	0.834	0.047
Scr umol/L	59.35 ± 13.42	60.21 ± 11.04	63.55 ± 24.02	0.690	0.638	0.452	0.553
UA umol/L	291.92 ± 70.12	300.87 ± 78.51	303.5 ± 71.07	0.611	0.397	0.489	0.893
UPH	6.04 ± 0.83	6.03 ± 0.62	5.92 ± 0.71	0.819	0.909	0.556	0.316
SG	1.02 ± 0.01	1.02 ± 0.01	1.01 ± 0.01	0.102	0.632	0.025	0.062

Data are presented as mean ± SD, n (%), median (IQR). Values were calculated using a t-test and χ2 test. BMI, Body mass index; WBC, White blood cell count; LYMPH, Lymphocyte count; NEUT, Neutrophil count; NLR, Neutrophil-to-lymphocyte ratio; UA, uric acid; Scr, Serum creatinine; HP, Hypertension; DM, Diabetes Mellitus; UPH, Urine pH; SG, Urine specific gravity; IC, Interstitial cystitis. * P < 0.05

ISSN: 1471-2490