Fig. 1

Construction of the co-expression network. a Sample clustering tree. b Analysis of the network topology of soft threshold power. Soft threshold (power = 3) and scale-free topology fit index (R2 = 0.85). c Tree diagram based on hierarchical clustering under optimal soft thresholds. d Correlation diagram between modules obtained by clustering according to inter-gene expression levels. e Heat map of the correlation between module characteristic genes and clinical features (normal and tumor). Correlations and p-values are provided for each module The values in the small cells of the graph represent the two-calculated correlation values cor coefficients between the eigenvalues of each trait and each module as well as the corresponding statistically significant p-values. Color corresponds to the size of the correlation; the darker the red, the more positive the correlation; the darker the green, the more negative the correlation