Fig. 2

Identification of differentially expressed genes (DEGs). a,b The volcano plot (a) and heatmap (b) of differentially expressed lncRNAs between KIRC samples and adjacent normal samples. Red denotes upregulated genes, and blue denotes downregulated genes in both volcano plots and heatmaps. The horizontal axis of the heatmaps represents the samples, and the vertical axis of heatmaps presents the top forty DEGs. c Correlation analysis of m7G-associated genes with lncRNAs. d The venn plot of KIRC-related modules lncRNAs (yellow), differentially expressed lncRNAs (pink) between KIRC and normal controls, and m7G-associated lncRNAs (green). e The volcano plot of 42 differentially expressed DE-m7G-realted lncRNAs. f Heat map for the expression of 42 DE-m7G-lncRNAs in normal kidney tissue and tumor tissue