Fig. 4

Independent prognostic analysis. a Patients with high expression of RP11-321G12.1 have reduced viability. b Reduced viability in patients with low PTCSC3 expression. c Univariate Cox regression analysis. d Multivariate Cox regression analysis. Forest plots show significant urvival-related factors based on univariate Cox regression analysis and multivariate Cox regression analyses. Note: P values were calculated by log-rank test. HR: hazard ratio; CI: confidence interval; ∗: P < 0.05; ∗∗: P < 0.01. e Nomogram combining clinicopathological variables and risk score. (f) Calibration curves of the nomogram for predicting survival at 1, 3, and 5 years. The nomogram prediction accuracy is higher if the actual curve is closer to the ideal curve. The gray dotted lines represent the ideal curve, and the blue, red, and green lines represent the actual curves for 1-year, 3-year, and 5-year survival rates. g Decision curve analysis (DCA) showing the clinical benefits of a predictive nomogram. h Clinical impact curve of nomogram. CIC visually shows that nomogram has high clinical net benefit and confirms the clinical value of nomogram