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TableĀ 5 Diagnostic efficiency of PI-RADS, biparametric model, and multiparametric model for csPCa

From: Values of multiparametric and biparametric MRI in diagnosing clinically significant prostate cancer: a multivariate analysis

Ā 

PIS

PRE1

PRE2

AUC (95% CI)

0.895 (0.868ā€“0.922)

0.918 (0.893ā€“0.940)

0.923 (0.898ā€“0.944)

Cut-off value

ā€‰>ā€‰3

ā€‰>ā€‰0.436

ā€‰>ā€‰0.390

Sensitivity (%)

78.99%

88.0%

87.32%

Specificity (%)

86.67%

83.2%

84.21%

Youden index

0.657

0.712

0.715

P value

ā€ƒPI-RADS

-

ā€‰<ā€‰0.0001

ā€‰<ā€‰0.0001

ā€ƒPRE1

ā€‰<ā€‰0.0001

-

0.0202

ā€ƒPRE2

ā€‰<ā€‰0.0001

0.0202

-

  1. PI-RADS Prostate imaging reporting and data system, csPCa clinically significant prostate cancer, AUC Area under the curve, PIS the 5-point results of PI-RADS v2.1 assessed by senior physicians, PRE1 the biparametric model involving ADC measured by bpMRI plus T2WI scores and PSAD, PRE2 the multiparametric model involving ADC measured by mpMRI plus PI-RADS scores and PSAD; ā€œ- ā€œ indicates not applicable