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Fig. 1 | BMC Urology

Fig. 1

From: The mechanism of PFK-1 in the occurrence and development of bladder cancer by regulating ZEB1 lactylation

Fig. 1

PFK-1 silencing inhibited BC progression. (A) The mRNA levels of PFK-1 were increased in SV-HUC-1, UM-UC-1, UM-UC-3, RT4, RT112, and T24 cells. UM-UC-1 and RT112 cells were used for next experiments. (B) After sh-PFK-1 transfection, the mRNA levels of PFK-1 in UM-UC-1 and RT112 cells was decreased. After sh-PFK-1 transfection, (C) CCK-8 assay indicated that cell viability of UM-UC-1 and RT112 cells was decreased. (D-E) Colony formation assay showed the cell growth of UM-UC-1 and RT112 cells were decreased. Transwell assay showed migration (F-G) and invasion (H-I) of UM-UC-1 and RT112 cells was decreased

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BMC Urology

ISSN: 1471-2490

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