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Fig. 3 | BMC Urology

Fig. 3

From: Elucidating the need for prostate cancer risk calculators in conjunction with mpMRI in initial risk assessment before prostate biopsy at a tertiary prostate cancer center

Fig. 3

ROC curves for csPCa detection by multivariate risk models and mpMRI in stratified subgroups based on mpMRI quality. ROC curve analysis of PI-RADS score, MRI-ERSPC-RC3, Radtke-RC, and MSP-RC before initial prostate biopsy comparing healthy patients and men with proven PCa (A, B) and csPCa (C, D) in men with quality-assured mpMRI (A, C) and men with mpMRI of uncertain quality (B, D) is illustrated. Absolute mean differences in AUC for mpMRI and mpMRI-derived risk models were 0.09 and 0.08 for PCa and 0.07 and 0.04 for csPCa. However, these AUC differences remained statistically insignificant for csPCa detection with an exception for Radtke-RC and MRI-ERSPC-RC3 in PCa detection (p = 0.032 and p = 0.033, respectively)

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