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Table 2 Detailed information of the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment results

From: Quantitative proteomic characterization of human sperm cryopreservation: using data-independent acquisition mass spectrometry

Pathway Name

Pathway ID

P value

Genes: Name|Ratio(Cryopreservated/Fresh)

Count

Pop Hit

Class

Ribosome

hsa03010

1.66E-06

RPL10A|0.573336532743;RPS19|0.631553739412;RPS13|0.523487855699;

RPL27|0.636693323276;RPS12|0.620311406135;RPS28|0.556462384813;

MRPS7|1.61901451638;RPL30|0.585111111172;RPL26|0.525298518938;

RPLP1|0.201692403302;RPS27|0.545857932715

11

138

Genetic Information Processing

Protein processing in endoplasmic reticulum

hsa04141

5.94E-05

CAPN1|0.483846314217;SEC63|1.64488179;NSFL1C|0.532234501825;

RAD23B|0.544847606418;RAD23A|0.449570898437;SEC61A2|1.59938044965;

SVIP|0.57175573788;SSR3|1.53947957741;SEC61G|12.6538069403;

RBX1|0.63561326146

10

166

Genetic Information Processing

Carbon metabolism

hsa01200

1.11E-04

GPI|0.594470429855;MUT|1.64145141153;ALDH6A1|1.80998863199;MDH1|0.61379399419;ADH5|1.57385688652;GLUD1|1.60104289531;PGAM1|0.554594456772;PCCB|1.67972523554

8

113

Metabolism

Protein export

hsa03060

2.07E-04

SEC63|1.64488179;SEC61A2|1.59938044965;SEC61G|12.6538069403;IMMP1L|1.67051120115

4

23

Genetic Information Processing

Propanoate metabolism

hsa00640

7.66E-04

MUT|1.64145141153;ALDH6A1|1.80998863199;LDHB|0.606365006071;PCCB|1.67972523554

4

32

Metabolism

Lysosome

hsa04142

1.13E-03

CTSF|0.624627283152;GNS|0.637102261894;ARSA|0.494575557376;NAGA|0.650162388685;NPC2|0.426290016224;AGA|0.43725788109;CLTA|0.666776335796

7

123

Cellular Processes

Cysteine and methionine metabolism

hsa00270

2.79E-03

AHCY|0.597470127607;MDH1|0.61379399419;LDHB|0.606365006071;GSS|0.585813890146

4

45

Metabolism

Glyoxylate and dicarboxylate metabolism

hsa00630

5.72E-03

MUT|1.64145141153;MDH1|0.61379399419;PCCB|1.67972523554

3

28

Metabolism

Glycolysis / Gluconeogenesis

hsa00010

1.15E-02

GPI|0.594470429855;LDHB|0.606365006071;ADH5|1.57385688652;PGAM1|0.554594456772

4

67

Metabolism

Pyruvate metabolism

hsa00620

1.54E-02

MDH1|0.61379399419;LDHB|0.606365006071;ACYP1|0.490664299807

3

40

Metabolism

Valine, leucine and isoleucine degradation

hsa00280

2.50E-02

MUT|1.64145141153;ALDH6A1|1.80998863199;PCCB|1.67972523554

3

48

Metabolism

Nucleotide excision repair

hsa03420

2.50E-02

RAD23B|0.544847606418;RAD23A|0.449570898437;RBX1|0.63561326146

3

48

Genetic Information Processing

Glutathione metabolism

hsa00480

3.08E-02

GSS|0.585813890146;GGCT|0.573964558442;GSTK1|1.70055565858

3

52

Metabolism

Proximal tubule bicarbonate reclamation

hsa04964

3.63E-02

MDH1|0.61379399419;GLUD1|1.60104289531

2

23

Organismal Systems

Parkinson’s disease

hsa05012

3.90E-02

ATP5F1|1.571159587;VDAC3|1.63594176768;UCHL1|0.613051768866;NDUFB8|1.71896191444;MT-ND3|1.54131079277

5

142

Human Diseases

Huntington’s disease

hsa05016

4.15E-02

DCTN2|0.634124905506;ATP5F1|1.571159587;VDAC3|1.63594176768;CLTA|0.666776335796;AP2S1|4.07535354503;NDUFB8|1.71896191444

6

193

Human Diseases

  1. The “Pop hit” is the total number of proteins in the pathway; the “Count “is the actually matched number
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BMC Urology

ISSN: 1471-2490

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