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  1. Detrusor overactivity (DO) secondary to partial bladder outlet obstruction (PBOO) is closely associated with alteration of ion channels. The objective of this study is to investigate the expression of the TWIK...

    Authors: Junlong Zhang, Mingxin Cao, Xilian Wu, Yu Chen, Weijie Liang and Yueyou Liang
    Citation: BMC Urology 2015 15:100
  2. Sarcosine has been investigated as a prostate cancer biomarker with mixed results concerning its predictive power. We performed a case–control evaluation of the predictive value of serum sarcosine for early de...

    Authors: Donna P. Ankerst, Michael Liss, David Zapata, Josef Hoefler, Ian M. Thompson and Robin J. Leach
    Citation: BMC Urology 2015 15:99
  3. Lymph node (LN) staging in penile cancer has strong prognostic implications. This contrasts with the high morbidity of extended inguinal LN dissection (LND) or over-treatment of many patients. Therefore, ingui...

    Authors: Tim Schubert, Jens Uphoff, Rolf-Peter Henke, Friedhelm Wawroschek and Alexander Winter
    Citation: BMC Urology 2015 15:98
  4. Genetically engineered mouse models are essential to the investigation of the molecular mechanisms underlying human prostate pathology and the effects of therapy on the diseased prostate. Serial in vivo volumetri...

    Authors: Shalini Singh, Chunliu Pan, Ronald Wood, Chiuan-Ren Yeh, Shuyuan Yeh, Kai Sha, John J. Krolewski and Kent L. Nastiuk
    Citation: BMC Urology 2015 15:97
  5. Recent studies showed that the non-adherence to the pharmacological therapy of patients affected by BPH-associated LUTS increased the risk of clinical progression of BPH. We examined the patients adherence to pha...

    Authors: Luca Cindolo, Luisella Pirozzi, Petros Sountoulides, Caterina Fanizza, Marilena Romero, Pietro Castellan, Alessandro Antonelli, Claudio Simeone, Andrea Tubaro, Cosimo de Nunzio and Luigi Schips
    Citation: BMC Urology 2015 15:96
  6. Male infertility is responsible for 50 % of infertile couples. Thirty percent of male infertility is due to cytogenetic and genetic abnormalities. In Arab and North African populations, several studies have sh...

    Authors: Yassine Naasse, Hicham Charoute, Brahim El Houate, Chadli Elbekkay, Lunda Razoki, Abderrahim Malki, Abdelhamid Barakat and Hassan Rouba
    Citation: BMC Urology 2015 15:95
  7. Radical prostatectomy is the most common and effective treatment for localized prostate cancer. Unfortunately, radical prostatectomy is associated with urinary incontinence and has a significant negative impac...

    Authors: Daniel Santa Mina, Darren Au, Shabbir M. H. Alibhai, Leah Jamnicky, Nelly Faghani, William J. Hilton, Leslie E. Stefanyk, Paul Ritvo, Jennifer Jones, Dean Elterman, Neil E. Fleshner, Antonio Finelli, Rajiv K. Singal, John Trachtenberg and Andrew G. Matthew
    Citation: BMC Urology 2015 15:94
  8. Benefits of simulation training are widely recognized, but its structural implementation into urological curricula remains challenging. This study aims to gain insight into current and ideal urological practic...

    Authors: Anna H. de Vries, Scheltus J. van Luijk, Albert J. J. A. Scherpbier, Ad J. M. Hendrikx, Evert L. Koldewijn, Cordula Wagner and Barbara M. A. Schout
    Citation: BMC Urology 2015 15:93
  9. To determine the incidence of later cancer detection and its risk factors after the first diagnostic ureteroscopy.

    Authors: Norihiro Murahashi, Takashige Abe, Nobuo Shinohara, Sachiyo Murai, Toru Harabayashi, Ataru Sazawa, Satoru Maruyama, Kunihiko Tsuchiya, Naoto Miyajima, Kanako Hatanaka and Katsuya Nonomura
    Citation: BMC Urology 2015 15:92
  10. To clarify the relationship between the probability of prostate cancer scaled using a 5-point Likert system and the biological characteristics of corresponding tumor foci.

    Authors: Taisuke Harada, Takashige Abe, Fumi Kato, Ryuji Matsumoto, Hiromi Fujita, Sachiyo Murai, Naoto Miyajima, Kunihiko Tsuchiya, Satoru Maruyama, Kohsuke Kudo and Nobuo Shinohara
    Citation: BMC Urology 2015 15:91
  11. The NIMA-related kinase 2 (NEK2) is a serine/threonine kinase that is involved in regulation of centrosome duplication and spindle assembly during mitosis. Dysregulation of these processes causes chromosome in...

    Authors: Yan-Ru Zeng, Zhao-Dong Han, Cong Wang, Chao Cai, Ya-Qiang Huang, Hong-Wei Luo, Ze-Zhen Liu, Yang-Jia Zhuo, Qi-Shan Dai, Hai-Bo Zhao, Yu-Xiang Liang and Wei-De Zhong
    Citation: BMC Urology 2015 15:90
  12. Terminal dribbling is one of the lower urinary tract symptoms (LUTS) that has not been widely studied. The aim of this study was to investigate the associations between terminal dribbling (TD) and other parame...

    Authors: Jae Heon Kim, Ji Sung Shim, Hoon Choi, Du Geon Moon, Jeong Gu Lee, Je Jong Kim, Jae Hyun Bae and Jae Young Park
    Citation: BMC Urology 2015 15:89
  13. PCA3 and TMPRSS2-ERG are commonly overexpressed biomarkers in prostate cancer, but reports have emerged demonstrating altered expression also in areas outside the tumour foci in cancerous prostates. Our aim was t...

    Authors: Riina-Minna Väänänen, Natalia Tong Ochoa, Peter J. Boström, Pekka Taimen and Kim Pettersson
    Citation: BMC Urology 2015 15:88
  14. We studied patients treated with radical cystectomy for locally advanced bladder cancer to compare the results of both preoperative positron emission tomography/computed tomography (PET/CT) and conventional CT...

    Authors: Firas Aljabery, Gunnar Lindblom, Susann Skoog, Ivan Shabo, Hans Olsson, Johan Rosell and Staffan Jahnson
    Citation: BMC Urology 2015 15:87
  15. Numerous studies indicated that Intravesical prostatic protrusion is relevant to prognosis of LUTS, however, the confounding effect that is brought about by prostate volume, urethra anterior curvature angle an...

    Authors: Junming Zheng, Jiangang Pan, Yi Qin, Jiale Huang, Yun Luo, Xin Gao and Xing Zhou
    Citation: BMC Urology 2015 15:86
  16. Existing epidemiological studies of the association between oxidative stress and erectile dysfunction (ED) are sparse and inconclusive, which is likely due to cross-sectional design and small sample size. Ther...

    Authors: Shuman Yang, Edward Giovannucci, Bruce Bracken, Shuk-Mei Ho and Tianying Wu
    Citation: BMC Urology 2015 15:85
  17. Hemophilia A is an X-linked recessive disorder caused by a deficiency in factor VIII. Hemophilia A affects 1 in 5,000–10,000 males. Hematuria is frequent in hemophilia. Hematuria in hemophilia is generally con...

    Authors: Satoshi Washino, Masaru Hirai, Yutaka Kobayashi, Kimitoshi Saito and Tomoaki Miyagawa
    Citation: BMC Urology 2015 15:84
  18. Impaired liver function in men can result in erectile dysfunction or hypogonadism or both. We investigated whether living donor liver transplantation (LDLT) results in improvement in male sexual function.

    Authors: You-Chiuan Chien, Heng-Chieh Chiang, Ping-Yi Lin and Yao-Li Chen
    Citation: BMC Urology 2015 15:83
  19. To identify the prevalence and clinical outcomes of pT0 disease following neoadjuvant hormonal therapy (NHT) and radical prostatectomy (RP) in high-risk prostate cancer.

    Authors: Jae Young Joung, Jeong Eun Kim, Sung Han Kim, Ho Kyung Seo, Jinsoo Chung, Weon Seo Park, Eun Kyung Hong and Kang Hyun Lee
    Citation: BMC Urology 2015 15:82
  20. Voiding dysfunctions are a common problem that has a severe negative impact on the quality of life. Today there is a need for new drug targets for these conditions. The role of ATP receptors in bladder physiol...

    Authors: Karl Svennersten, Katarina Hallén-Grufman, Petra J. de Verdier, N. Peter Wiklund and Mirjana Poljakovic
    Citation: BMC Urology 2015 15:81
  21. Given that a deubiquitinating enzyme, ubiquitin-specific protease 2a (USP2a), regulates ubiquitination, trafficking, and degradation of EGFR, which plays a critical role in bladder cancer, in this study, we ai...

    Authors: Pildu Jeong, Yun-Sok Ha, Seok-Joong Yun, Hyung Yoon Yoon, Michael R. Freeman, Jayoung Kim and Wun-Jae Kim
    Citation: BMC Urology 2015 15:80
  22. The presence of lymph nodes (LN) within the prostatic anterior fat pad (PAFP) has been reported in several recent reports. These PAFP LNs rarely harbor metastatic disease, and the characteristics of patients w...

    Authors: Young Suk Kwon, Yun-Sok Ha, Parth K. Modi, Amirali Salmasi, Jaspreet S. Parihar, Neal Patel, Izak Faiena, Michael May, David I. Lee, Elton Llukani, Tuliao Patrick, Koon Ho Rha, Thomas Ahlering, Douglas Skarecky, Hanjong Ahn, Seung-Kwon Choi…
    Citation: BMC Urology 2015 15:79
  23. The aim of this study was to investigate whether we could detect positive surgical margins during open and laparoscopic radical prostatectomy by 5-aminolevulinic acid (ALA) photodynamic diagnosis (PDD) and map...

    Authors: Hideo Fukuhara, Keiji Inoue, Atsushi Kurabayashi, Mutsuo Furihata and Taro Shuin
    Citation: BMC Urology 2015 15:78
  24. The optimal timing of catheter removal following laparoscopic radical prostatectomy (LRP) has not yet been determined. This prospective study was designed to compare the efficacy and safety of catheter removal...

    Authors: Masashi Matsushima, Akira Miyajima, Seiya Hattori, Toshikazu Takeda, Ryuichi Mizuno, Eiji Kikuchi and Mototsugu Oya
    Citation: BMC Urology 2015 15:77
  25. An imaging tool providing reliable prostate cancer (PCa) detection and localization is necessary to improve common diagnostic pathway with ultrasound targeted biopsies. To determine the performance of transrec...

    Authors: Moritz Franz Hamann, C. Hamann, A. Trettel, K P Jünemann and C M Naumann
    Citation: BMC Urology 2015 15:76
  26. Autoimmune hemolytic anemia (AIHA) is hemolytic anemia characterized by autoantibodies directed against red blood cells. AIHA can be induced by hematological neoplasms such as malignant lymphoma, but is rarely...

    Authors: Shuji Isotani, Akira Horiuchi, Masayuki Koja, Takahiro Noguchi, Shouichiro Sugiura, Hirofumi Shimoyama, Yasuhiro Noma, Kousuke Kitamura, Toshiyuki China, Shino Tokiwa, Keisuke Saito, Masaki Kimura, Shin-ichi Hisasue, Hisamitsu Ide, Satoru Muto, Raizo Yamaguchi…
    Citation: BMC Urology 2015 15:75
  27. Nutcracker syndrome is an entity resulting from left renal vein compression by the aorta and the superior mesenteric artery, which leads to symptoms of hematuria or left flank pain. The alternative option of e...

    Authors: Lu Tian, Shanwen Chen, Gaoyue Zhang, Hongkun Zhang, Wei Jin and Ming Li
    Citation: BMC Urology 2015 15:73
  28. Shock wave lithotripsy (SWL) is a noninvasive, safe, and efficient treatment option for ureteral stones. Depending on stone location and size, the overall stone-free rate (SFR) varies significantly. Failure of...

    Authors: Gautier Müllhaupt, Daniel S. Engeler, Hans-Peter Schmid and Dominik Abt
    Citation: BMC Urology 2015 15:72
  29. Urologists use biopsy Gleason scores for patient counseling, prognosis prediction, and decision making. The accuracy of Gleason grading is very important. However, the variability of Gleason grading between ge...

    Authors: Yasushi Nakai, Nobumichi Tanaka, Keiji Shimada, Noboru Konishi, Makito Miyake, Satoshi Anai and Kiyohide Fujimoto
    Citation: BMC Urology 2015 15:70
  30. Primary melanoma of the prostate has an extremely rare incidence. Only five cases have been reported in the literature and prognosis is poor. The most likely origin of prostatic melanoma is the transitional ep...

    Authors: Georgi Tosev, Timur H. Kuru, Johannes Huber, Gerald Freier, Frank Bergmann, Jessica C. Hassel, Sascha A. Pahernik, Markus Hohenfellner and Boris A. Hadaschik
    Citation: BMC Urology 2015 15:68
  31. A new serum marker of inflammation copeptin (CPP) a stable C-terminal pro-vasopressin was assessed along with conventional markers such as C-reactive protein (CRP), procalcitonin (PCT) and IL-6 to discriminate...

    Authors: Anna Masajtis-Zagajewska, Ilona Kurnatowska, Malgorzata Wajdlich and Michal Nowicki
    Citation: BMC Urology 2015 15:67
  32. Radiotherapy is one of the treatment options for prostate cancer (PCa) but up to 25 % of men report about severe nocturia (nocturnal voiding). The combination of hyaluronic acid (HA) and chondroitin sulfate (C...

    Authors: Mauro Gacci, Omar Saleh, Claudia Giannessi, Beatrice Detti, Lorenzo Livi, Eleonora Monteleone Pasquetti, Tatiana Masoni, Enrico Finazzi Agro, Vincenzo Li Marzi, Andrea Minervini, Marco Carini, Stavros Gravas, Matthias Oelke and Sergio Serni
    Citation: BMC Urology 2015 15:65
  33. The study on SIMS and SMUS as a whole by Alyaa Mostafa et al showed that after excluding the TVT-S sling, there is no significant difference in patient-reported cure rate and objective cure rate between these ...

    Authors: Peng Zhang, Bohan Fan, Peng Zhang, Hu Han, Yue Xu, Biao Wang and Xiaodong Zhang
    Citation: BMC Urology 2015 15:64
  34. We performed a pilot study using a single virtual-simulation suturing module as an objective measurement to determine functional use of the robotic system. This study will assist in designing a study for an ob...

    Authors: Michael A. Liss, Christopher J. Kane, Tony Chen, Joel Baumgartner and Ithaar H. Derweesh
    Citation: BMC Urology 2015 15:63
  35. Vesicourethral anastomotic stricture (VAS) is a rare but serious complication following radical prostatectomy (RP), and various types of managements for VAS have been proposed. We investigated the efficacy of ...

    Authors: Gen Ishii, Takehito Naruoka, Kanako Kasai, Kenichi Hata, Hiroshi Omono, Masayasu Suzuki, Takahiro Kimura and Shin Egawa
    Citation: BMC Urology 2015 15:62
  36. Little is known about the healthcare process for patients with prostate cancer, mainly because hospital-based data are not routinely published. The main objective of this study was to determine the clinical ch...

    Authors: Xavier Bonfill, María José Martinez-Zapata, Robin WM Vernooij, María José Sánchez, María Morales Suárez-Varela, Javier de la Cruz, José Ignacio Emparanza, Montserrat Ferrer, José Ignacio Pijoán, Juan M. Ramos-Goñi, Joan Palou, Stefanie Schmidt, Víctor Abraira and Javier Zamora
    Citation: BMC Urology 2015 15:60
  37. We sought to examine differences in response rates to quality of life (QoL) surveys in patients treated surgically for renal cell carcinoma (RCC) and prostate cancer (PCa) and to analyze factors associated wit...

    Authors: David D. Thiel, Andrew J. Davidiuk, Gregory A. Broderick, Michelle Arnold, Nancy Diehl, Andrea Tavlarides, Kaitlynn Custer and Alexander S. Parker
    Citation: BMC Urology 2015 15:58
  38. Little is known about the biological behavior of Xp11.2 translocation renal cell carcinomas (RCCs) as few clinical studies have been performed using a large sample size.

    Authors: Linfeng Xu, Rong Yang, Weidong Gan, Xiancheng Chen, Xuefeng Qiu, Kai Fu, Jin Huang, Guancheng Zhu and Hongqian Guo
    Citation: BMC Urology 2015 15:57
  39. This study was carried out a network meta-analysis of evidence from randomized controlled trials (RCTs) to evaluate stent-related discomfort in patients with alfuzosin or tamsulosin versus placebo.

    Authors: Jong Kyou Kwon, Kang Su Cho, Cheol Kyu Oh, Dong Hyuk Kang, Hyungmin Lee, Won Sik Ham, Young Deuk Choi and Joo Yong Lee
    Citation: BMC Urology 2015 15:55
  40. To investigate associations between dual-specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) expression and survival in T1 high-grade or T2 bladder cancer patients treated with neoadjuvant chemothe...

    Authors: Shunichiro Nomura, Yasutomo Suzuki, Ryo Takahashi, Mika Terasaki, Ryoji Kimata, Yasuhiro Terasaki, Tsutomu Hamasaki, Go Kimura, Akira Shimizu and Yukihiro Kondo
    Citation: BMC Urology 2015 15:53
  41. Active surveillance is considered a mainstream strategy in the management of patients with low-risk prostate cancer. A mission-critical step in implementing a robust active surveillance program and plan its re...

    Authors: Yiannis Philippou, Hary Raja and Vincent J. Gnanapragasam
    Citation: BMC Urology 2015 15:52

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