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  1. Radical prostatectomy is a standard surgical treatment of clinically localized prostate cancer. Margin status has been found to be an independent predictor of biochemical recurrence (BCR) after open radical pr...

    Authors: Ryuta Tanimoto, Yomi Fashola, Kymora B Scotland, Anne E Calvaresi, Leonard G Gomella, Edouard J Trabulsi and Costas D Lallas
    Citation: BMC Urology 2015 15:27
  2. A previous study showed that foot stimulation can delay the bladder filling sensation and increase bladder volume in healthy humans without OAB. The aim of this study was to determine whether or not electrical...

    Authors: Guoqing Chen, Limin Liao and Di Miao
    Citation: BMC Urology 2015 15:26
  3. To assess pathological correlations and temporal trends of Angiopoietin-2 (ANGPT2), vascular endothelial growth factor (VEGF) and M2 Pyruvate kinase (TuM2PK), markers of tumor vascular development and metaboli...

    Authors: Bishoy A Gayed, Jessica Gillen, Alana Christie, Samuel Peña-Llopis, Xian-Jin Xie, Jingsheng Yan, Jose A Karam, Ganesh Raj, Arthur I Sagalowsky, Yair Lotan, Vitaly Margulis and James Brugarolas
    Citation: BMC Urology 2015 15:24
  4. Hematuria can be symptomatic of urothelial carcinoma (UC) and ruling out patients with benign causes during primary evaluation is challenging. Patients with hematuria undergoing urological work-ups place signi...

    Authors: Laimonis Kavalieris, Paul J O’Sullivan, James M Suttie, Brent K Pownall, Peter J Gilling, Christophe Chemasle and David G Darling
    Citation: BMC Urology 2015 15:23
  5. Ipsilateral asymptomatic renal stone associated with symptomatic ureteral stone is not a rare event, and the recommended treatment policy was not declared clearly. This study was conducted to compare the outco...

    Authors: Dehui Lai, Meiling Chen, Yongzhong He and Xun Li
    Citation: BMC Urology 2015 15:22
  6. Major life-threatening complications secondary to cisplatin-based chemotherapy are rare in patients with testicular germ cell tumour (GCT). The incidence of complications increases with dosage of chemotherapy ...

    Authors: Klaus-Peter Dieckmann, Petra Anheuser, Ralf Gehrckens, Sven Philip Aries, Raphael Ikogho and Wiebke Hollburg
    Citation: BMC Urology 2015 15:21
  7. Metastasis to penis usually arises from genitourinary organs, but in rare cases, metastasis comes from the sigmoid colon. Furthermore, very few cases of penile metastasis of primary sigmoid colon carcinoma hav...

    Authors: Zhengbang Dong, Chao Qin, Qijie Zhang, Lei Zhang, Haijing Yang, Jingdong Zhang and Fei Wang
    Citation: BMC Urology 2015 15:20
  8. Although there is growing evidence of relationship between obesity and some specific stone compositions, results were inconsistent. Due to a greater relationship between metabolic syndrome and some specific st...

    Authors: Jae Heon Kim, Seung Whan Doo, Kang Su Cho, Won Jae Yang, Yun Seob Song, Jiyoung Hwang, Seong Sook Hong and Soon-Sun Kwon
    Citation: BMC Urology 2015 15:17
  9. The loss of a testicle to cancer involves much emotional impact to young males. Little is known about the number of patients with testicular germ cell tumour (GCT) who would accept a testicular prosthesis. Als...

    Authors: Klaus-Peter Dieckmann, Petra Anheuser, Stefan Schmidt, Benjamin Soyka-Hundt, Uwe Pichlmeier, Philipp Schriefer, Cord Matthies, Michael Hartmann and Christian G Ruf
    Citation: BMC Urology 2015 15:16
  10. More than 429,000 patients worldwide are diagnosed with bladder cancer each year and muscle-invasive bladder cancer has an especially poor outcome. The median age at diagnosis is over 70 years, and many patien...

    Authors: Vicente Guillem, Miguel Angel Climent, Javier Cassinello, Emilio Esteban, Daniel Castellano, José Luis González-Larriba, Pablo Maroto and Carlos Camps
    Citation: BMC Urology 2015 15:15
  11. The human papillomavirus (HPV) prevalence in males has been reported to be between 3.6% and 84%, depending specially on the socioeconomic status. HPV infection has been related as a risk factor for penile canc...

    Authors: Isaura Danielli Borges de Sousa, Flávia Castello Branco Vidal, João Paulo Castello Branco Vidal, George Castro Figueira de Mello, Maria do Desterro Soares Brandão Nascimento and Luciane Maria Oliveira Brito
    Citation: BMC Urology 2015 15:13
  12. Currently, men are younger at the time of diagnosis of prostate cancer and more interested in less invasive surgical approaches (traditional laparoscopy, 3D-laparoscopy, robotics). Outcomes of continence, erec...

    Authors: Pierluigi Bove, Valerio Iacovelli, Francesco Celestino, Francesco De Carlo, Giuseppe Vespasiani and Enrico Finazzi Agrò
    Citation: BMC Urology 2015 15:12
  13. In this paper, we observed a discrepancy of penile hemodynamics dependent on location by using near infrared spectroscopy (NIRS) sensor, and showcase NIRS as a potentially suitable sensor in supplementing the ...

    Authors: Evgenii Kim, Songhyun Lee, Zephaniah Phillips V and Jae G Kim
    Citation: BMC Urology 2015 15:11
  14. Choline positron emission tomography/computed tomography (PET/CT) represents an option in restaging of prostate cancer patients with disease relapse after local treatment. The present study assess whether salv...

    Authors: Alexander Winter, Rolf-Peter Henke and Friedhelm Wawroschek
    Citation: BMC Urology 2015 15:10
  15. The treatment of large volume bladder stones by current equipments continues to be a management problem in both developing and developed countries. AH-1 Stone Removal System (SRS) invented by us is primarily u...

    Authors: Aihua Li, Chengdong Ji, Hui Wang, Genqiang Lang, Honghai Lu, Sikuan Liu, Weiwu Li, Binghui Zhang and Wei Fang
    Citation: BMC Urology 2015 15:9
  16. We produced a novel model of bladder outlet obstruction (BOO) by periurethral injection of hyaluronic acid and compared the cystometric features, postoperative complications, and histopathological changes of t...

    Authors: Yongquan Wang, Zhiyong Xiong, Wei Gong, Zhansong Zhou and Gensheng Lu
    Citation: BMC Urology 2015 15:8
  17. Adenosine-5′-triphosphate (ATP) is a neurotransmitter and inflammatory cytokine implicated in the pathophysiology of lower urinary tract disease. ATP additionally reflects microbial biomass thus has potential ...

    Authors: Kiren Gill, Harry Horsley, Anthony S Kupelian, Gianluca Baio, Maria De Iorio, Sanchutha Sathiananamoorthy, Rajvinder Khasriya, Jennifer L Rohn, Scott S Wildman and James Malone-Lee
    Citation: BMC Urology 2015 15:7
  18. Tramadol is a centrally acting analgesic prescribed off-label for the treatment of premature ejaculation (PE). However, tramadol may cause addiction and difficulty in breathing and the beneficial effect of tra...

    Authors: Marrissa Martyn-St James, Katy Cooper, Eva Kaltenthaler, Kath Dickinson, Anna Cantrell, Kevan Wylie, Leila Frodsham and Catherine Hood
    Citation: BMC Urology 2015 15:6
  19. Adenocarcinoma of the urinary bladder is a rare malignancy. Radical surgery is suggested as the best available treatment for early-stage disease, but there is currently no consensus on standard chemotherapy re...

    Authors: Bin Yu, Jin Zhou, Hongzhou Cai, Ting Xu, Zicheng Xu, Qing Zou and Min Gu
    Citation: BMC Urology 2015 15:3
  20. To investigate the expression of parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor 1 (PTH1R) in clinical specimens of normal and diseased bladders. PTHrP is a unique stretch-induced endogenous det...

    Authors: Nobuyuki Nishikawa, Rie Yago, Yuichiro Yamazaki, Hiromitsu Negoro, Mari Suzuki, Masaaki Imamura, Yoshinobu Toda, Kazunari Tanabe, Osamu Ogawa and Akihiro Kanematsu
    Citation: BMC Urology 2015 15:2
  21. 46,XX testicular disorder of sex development is a rare genetic syndrome, characterized by a complete or partial mismatch between genetic sex and phenotypic sex, which results in infertility because of the abse...

    Authors: Tian-Fu Li, Qiu-Yue Wu, Cui Zhang, Wei-Wei Li, Qing Zhou, Wei-Jun Jiang, Ying-Xia Cui, Xin-Yi Xia and Yi-Chao Shi
    Citation: BMC Urology 2014 14:104
  22. Aim of this study was to make a comparison between penile cuff test (PCT) and standard pressure-flow study (PFS) in the preoperative evaluation of patients candidates for trans-urethral resection of prostate (...

    Authors: Daniele Bianchi, Angelo Di Santo, Gabriele Gaziev, Roberto Miano, Stefania Musco, Giuseppe Vespasiani and Enrico Finazzi Agrò
    Citation: BMC Urology 2014 14:103
  23. Papillary renal cell carcinoma (pRCC) is a mixed group of tumors that constitutes about 15-20% of all renal cortical cancers. Strong enhancement on computerized tomography (CT) is a feature of clear cell, but ...

    Authors: Shaheen Alanee, Danuta I Dynda, Patrick Hemmer and Bradley Schwartz
    Citation: BMC Urology 2014 14:102
  24. Partial nephrectomy has been underutilized in the United States. We investigated national trends in partial nephrectomy (PN) utilization before and after publication of the American Urological Association (AUA...

    Authors: Michael A Liss, Song Wang, Kerrin Palazzi, Ramzi Jabaji, Nishant Patel, Hak J Lee, J Kellogg Parsons and Ithaar H Derweesh
    Citation: BMC Urology 2014 14:101
  25. Partial segmental thrombosis of the corpus cavernosum (PSTCC) is a rare disease predominantly occurring in young men. Cardinal symptoms are pain and perineal swelling. Although several risk factors are describ...

    Authors: Stephanie Sauer, Jan P Goltz, Tobias Gassenmaier, Andreas S Kunz, Thorsten A Bley, Detlef Klein and Bernhard Petritsch
    Citation: BMC Urology 2014 14:100
  26. Radical prostatectomy (RP) is the most common treatment for patients with localized prostate cancer. Urinary incontinence (UI) is a significant bothersome sequela after radical prostatectomy that may dramatica...

    Authors: Wei Wang, Qing Mei Huang, Feng Ping Liu and Qi Qi Mao
    Citation: BMC Urology 2014 14:99
  27. Black men with prostate cancer are diagnosed at a younger age, present with more aggressive disease, and experience higher mortality. We sought to assess pathological features and biochemical recurrence (BCR) ...

    Authors: Kelvin A Moses, Ling Y Chen, Daniel D Sjoberg, Melanie Bernstein and Karim A Touijer
    Citation: BMC Urology 2014 14:98
  28. There is paucity of data as to the results of the endoscopic approach in comparison to the golden standard of nephro-ureterectomy in elective, low grade TCC, patients. Our purpose is to report our results of a...

    Authors: Azik Hoffman, Ofer Yossepowitch, Yaron Erlich, Ronen Holland and David Lifshitz
    Citation: BMC Urology 2014 14:97
  29. Acute hypokalaemic paralysis is characterised by acute flaccid muscle weakness and has a complex aetiological spectrum. Herein we report, for the first time, a case of unilateral adrenal hyperplasia accompanie...

    Authors: Bo Yang, Yuan Yang, Wenling Tu, Ying Shen and Qiang Dong
    Citation: BMC Urology 2014 14:96
  30. To determine the relationship between renal cell carcinoma subtypes and the associated mortality and biochemical parameters. An additional aim was to analyze multiphasic multidetector computed tomography findi...

    Authors: Suat Keskin, Zeynep Keskin, Hakan Hakki Taskapu, Havva Kalkan, Mehmet Kaynar, Necdet Poyraz and Hatice Toy
    Citation: BMC Urology 2014 14:95
  31. Benign prostatic hyperplasia (BPH) is a prevalent entity in elderly men and transurethral resection of the prostate (TURP) still represents the gold standard of surgical treatment despite its considerable peri...

    Authors: Dominik Abt, Livio Mordasini, Lukas Hechelhammer, Thomas M Kessler, Hans-Peter Schmid and Daniel S Engeler
    Citation: BMC Urology 2014 14:94
  32. Urethrocutaneous fistulae (UCFs) represent one of the most frequent causes of morbidity after urethroplasty. Hypospadias can be repaired using different surgical techniques, but—regardless of technique—the inc...

    Authors: Gabriela Ambriz-González, Pedro Aguirre-Ramirez, José Manuel García-de León, Francisco Javier León-Frutos, Sergio Adrián Montero-Cruz, Xóchilt Trujillo, Clotilde Fuentes-Orozco, Michel Dassaejv Macías-Amezcua, Andrea del Socorro Álvarez-Villaseñor, Ana Olivia Cortés-Flores, Mariana Chávez-Tostado and Alejandro González-Ojeda
    Citation: BMC Urology 2014 14:93
  33. In patients with localized high-risk prostate cancer awaiting radiation therapy, pelvic lymphadenectomy (PL) is a reliable minimally invasive staging procedure. We compared outcomes after laparoendoscopic sing...

    Authors: Frank Friedersdorff, Seven Johannes Aghdassi, Ahmed Magheli, Maximilian Richter, Carsten Stephan, Jonas Busch, Dirk Boehmer, Kurt Miller and T Florian Fuller
    Citation: BMC Urology 2014 14:92
  34. Irrigation or washouts of the bladder are usually performed in various clinical settings. In the 1980s Elliot and colleagues argued that urothelial damage could occur after washouts and irrigations of the blad...

    Authors: Marco Di Paolo, Valentina Bugelli, Alessandro Di Luca and Emanuela Turillazzi
    Citation: BMC Urology 2014 14:91
  35. Cystoscopy evokes discomfort and pain, especially in males. The cystoscopic retrograde approach is standard in the removal of ureteral stents. However the satisfaction and degree of pain during the procedure a...

    Authors: Jae Heon Kim, Sun Young Park, Mun Gyu Kim, Hoon Choi, Dan Song, Sung Woo Cho and Yun Seob Song
    Citation: BMC Urology 2014 14:90
  36. Radical cystectomy with pelvic lymph node dissection represents the standard treatment for muscle-invasive, and high-risk non-muscle-invasive bladder cancers. Aim of this study was to report our case series of...

    Authors: Antonio Luigi Pastore, Giovanni Palleschi, Luigi Silvestri, Giuseppe Cavallaro, Mario Rizzello, Gianfranco Silecchia, Cosimo de Nunzio, Samer Fathi Al-Rawashdah, Vincenzo Petrozza and Antonio Carbone
    Citation: BMC Urology 2014 14:89
  37. Acanthosis nigricans is characterized by hyperpigmentation and hyperkeratosis of the skin or mucous membranes. Its malignant form is associated with internal neoplasms, especially gastric adenocarcinoma (55–61...

    Authors: Joanna Kubicka-Wołkowska, Sylwia Dębska-Szmich, Maja Lisik-Habib, Marcin Noweta and Piotr Potemski
    Citation: BMC Urology 2014 14:88
  38. Cystic renal cell carcinoma (CRCC) is relatively rare; CRCC is frequently misdiagnosed as a benign renal cyst. CRCC carries an excellent prognosis following surgical treatment. The aim of our study was to summ...

    Authors: Shanwen Chen, Baiye Jin, Liqi Xu, Guanghou Fu, Hongzhou Meng, Ben Liu, Jun Li and Dan Xia
    Citation: BMC Urology 2014 14:87
  39. The objective of this population-based study was to assess patient, physician and tumour determinants associated with positive surgical margins after prostatectomy, and to assess the effects of positive surgic...

    Authors: Valesca P Retèl, Christine Bouchardy, Massimo Usel, Isabelle Neyroud-Caspar, Franz Schmidlin, Gregory Wirth, Christophe Iselin, Raymond Miralbell and Elisabetta Rapiti
    Citation: BMC Urology 2014 14:86
  40. The causality of overactive bladder syndrome (OAB) is still not fully understood. Several studies indicate a significant increase of prostaglandin E2 (PGE2) in patients with OAB. However, in order to clarify w...

    Authors: Axel Hegele, Sonja Knippschild, Carsten Frohme, Jörg Hänze, Peter Olbert and Rainer Hofmann
    Citation: BMC Urology 2014 14:85
  41. Overactive bladder (OAB)/ storage lower urinary tract symptoms (LUTS) have a high prevalence affecting up to 90% of men over 80 years. The role of sufficient therapies appears crucial. In the present review, w...

    Authors: Mauro Gacci, Giacomo Novara, Cosimo De Nunzio, Andrea Tubaro, Riccardo Schiavina, Eugenio Brunocilla, Arcangelo Sebastianelli, Matteo Salvi, Matthias Oelke, Stavros Gravas, Marco Carini and Sergio Serni
    Citation: BMC Urology 2014 14:84
  42. Laparo Endoscopic Single-site Surgery (LESS) represents an evolution of minimally invasive surgery and aims to improve cosmetic outcome and reduce surgical trauma and complications associated with traditional ...

    Authors: Salvatore Micali, Ahmed Ghaith, Eugenio Martorana, Alessio Zordani, Angelo Territo and Giampaolo Bianchi
    Citation: BMC Urology 2014 14:83
  43. Radical prostatectomy (RP) is a common treatment for prostate cancer (PCa). Morbidity, mortality and pathological outcomes may be superior in academic institutions. One explanation may be the involvement of on...

    Authors: Jasmir G Nayak, Darrel E Drachenberg, Elke Mau, Derek Suderman, Oliver Bucher, Pascal Lambert and Harvey Quon
    Citation: BMC Urology 2014 14:82

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