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  1. Bladder cancer, one of the most prevalent malignant cancers, has high rate of recurrence and metastasis. Owing to genomic instability and high-level heterogeneity of bladder cancer, chemotherapy and immunother...

    Authors: Zeyi Wang, Zhengnan Huang, Xiangqian Cao, Fang Zhang, Jinming Cai, Pengfei Tang, Chenkai Yang, Shengzhou Li, Dong Yu, Yilin Yan and Bing Shen
    Citation: BMC Urology 2023 23:10
  2. The high incidence of Gleason score upgrading (GSU) made urologists underestimate the disease, leading to the inaccurate therapeutic decision. The study aimed to explore relevant laboratory examination evidenc...

    Authors: Jingcheng Lyu, Lu Li, Tianyu Jiang, Zhipeng Wang and Yichen Zhu
    Citation: BMC Urology 2023 23:8
  3. Repair of long-segment ureteral defect (LSUD) is challenging. Currently available procedures carry some potential complications. We modified the ileal graft by tapering the wall and stripping the mucosa to com...

    Authors: Shulian Chen, Yu Jian, Wen Tang, Hao Gu, Kebing Luo, Denghao Yang, Huihui Xie, Guobiao Liang and Zeju Zhao
    Citation: BMC Urology 2023 23:7
  4. To evaluate the incidence of lymph node degeneration and its association with nodal metastatic pattern in prostate cancer.

    Authors: Daniel Gödde, Stephan Degener, Christine Walles, Rosalie Keller, Nici Markus Dreger, Katharina Graf, Friedrich-Carl von Rundstedt, Hans Michael Kvasnicka, Susanne Krege and Stephan Störkel
    Citation: BMC Urology 2023 23:6
  5. Current research on the posterior urethral valve (PUV) mainly focuses on the follow-up of bladder function after valve ablation. However, few studies exist on the changes in bladder function before and after v...

    Authors: Zhiqiang Mo, Minglei Li, Xianghui Xie, Ning Sun, Weiping Zhang, Jun Tian and Hongcheng Song
    Citation: BMC Urology 2023 23:5
  6. There is a paucity of information on the use of novel hormonal agents in Southeast Asian patients. We reviewed the clinical roles of novel hormonal therapy (NHT), namely abiraterone acetate (AA), enzalutamide,...

    Authors: Teng Aik Ong, Marniza Saad, Jasmine Lim and Hsien Hooi Lee
    Citation: BMC Urology 2023 23:4
  7. To evaluate the role of preoperative UWT in the prediction of impaction of ureteral stones stratified according to stone size in ureteroscopic laser lithotripsy.

    Authors: Abdrabuh M. Abdrabuh, El-Sayed I. El-Agamy, Mohamed A. Elhelaly, Tamer A. Abouelgreed, Ibrahim Abdel-Al, Hamada A. Youssof, Adel Elatreisy, Osama Shalkamy, Mohamed Elebiary, Mohammed Agha, Ibrahim Tagreda, Ahmed Alrefaey and Elsayed Elawadey
    Citation: BMC Urology 2023 23:3
  8. To establish a prognostic nomogram among UTUC patients who received chemotherapy.

    Authors: Cong Tian, Jun Liu, Lizhe An, Yang Hong and Qingquan Xu
    Citation: BMC Urology 2023 23:2

    The Correction to this article has been published in BMC Urology 2023 23:110

  9. Urethral stenosis caused by pelvic fracture urethral injury (PFUI) is a complex urological disease, especially for the redo cased. However, to find the proximal end of the posterior urethra, and to avoid injur...

    Authors: Kaile Zhang, Jiafu Liu, Liyang Wang, Wenyao Li, Er Qi and Qiang Fu
    Citation: BMC Urology 2023 23:1
  10. Urinary incontinence (UI) is one of the most common problems in old age that is often seen in women, which causes not only physical problems but also psychological, social, economic problems and poor quality o...

    Authors: Zahra Najafi, Mohammad Ali Morowatisharifabad, Sara Jambarsang, Hassan Rezaeipandari and Roya Hemayati
    Citation: BMC Urology 2022 22:214
  11. In this study we investigated the expression of vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR) and prostate-specific membrane antigen (PSMA) to analyze their potency as targ...

    Authors: Christa Anne Maria van der Fels, Annemarie Leliveld, Henk Buikema, Marius Christianus van den Heuvel and Igle Jan de Jong
    Citation: BMC Urology 2022 22:213
  12. Urothelial carcinoma is the most common type of bladder cancer worldwide and it has a poor prognosis for patients with distant metastasis. Nomograms are frequently used in clinical research, but no research ha...

    Authors: Di Chen, Zhihua Luo, Chaoping Ye, Quanhai Luo, Wenji Fan, Changsheng Chen and Gang Liu
    Citation: BMC Urology 2022 22:212
  13. To assess the characteristics, predictive risk factors, and prognostic effect of secondary bladder cancer (SBCa) following radical nephroureterectomy (RNU) in upper tract urothelial carcinoma (UTUC).

    Authors: Shicong Lai, Pengjie Wu, Shengjie Liu, Samuel Seery, Jianyong Liu, Lei He, Ming Liu, Yaoguang Zhang, Jian-ye Wang and Tao Xu
    Citation: BMC Urology 2022 22:211
  14. Different pathological types of testicular tumors are treated differently. Malignant germ cell tumors require radical orchiectomy, while benign tumors may only need mass enucleation. Contrast-enhanced ultrason...

    Authors: Nianyu Xue, Shengmin Zhang and Guoyao Wang
    Citation: BMC Urology 2022 22:210
  15. Day-surgery percutaneous nephrolithotomy (PCNL) is being developed quickly but some potential factors are affecting the recovery process. This study is aim to analyze the reasons and risk factors for delayed d...

    Authors: Huacai Zhu, Bangfeng Liu, Mehmet Ali Karagöz, Gaoyuanzhi Yue, Yeci Lei, Shangwen Dou, Zhanping Xu and Yongda Liu
    Citation: BMC Urology 2022 22:209
  16. We compared the intraoperative and postoperative outcomes of robotic-assisted laparoscopic partial nephrectomy (RALPN) via transabdominal or retroperitoneal approaches in patients with stage T1b renal cell car...

    Authors: Hao Tang, Tianyi Shen, Kai Zhou, Feng Xu, Huichen Lv and Jingping Ge
    Citation: BMC Urology 2022 22:208
  17. The urachus is an embryonic structure that connects the bladder to the allantois during early embryonic development. Occasionally, it fails to disappear at birth, leading to a case of urachal remnant (UR). Thi...

    Authors: Yoichi Nakagawa, Wataru Sumida, Hizuru Amano, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Satoshi Makita, Masamune Okamoto, Seiya Ogata, Aitaro Takimoto, Shunya Takada, Daiki Kato and Yousuke Gohda
    Citation: BMC Urology 2022 22:207
  18. The RCC treatment landscape has evolved dramatically over the past decade. The purpose of this study is to present a real-world data estimation of RCC’s cost-of-illness for this tumour’s clinical pathway.

    Authors: Alessandra Buja, Giuseppe De Luca, Maura Gatti, Claudia Cozzolino, Massimo Rugge, Manuel Zorzi, Mario Gardi, Matteo Sepulcri, Davide Bimbatti, Vincenzo Baldo, Marco Maruzzo, Umberto Basso and Vittorina Zagonel
    Citation: BMC Urology 2022 22:206
  19. Kidney stone is the major cause of morbidity, and its prevalence is increasing in the world. This study aimed to assess the prevalence and risk factors of kidney stone in the adult population of southern Iran ...

    Authors: Leila Moftakhar, Fatemeh Jafari, Masoumeh Ghoddusi Johari, Ramin Rezaeianzadeh, Seyed Vahid Hosseini and Abbas Rezaianzadeh
    Citation: BMC Urology 2022 22:205
  20. A nadir Prostate-Specific Antigen (nPSA) of 0.06 ng/mL has been shown to be a strong independent predictor of biochemical recurrence-free survival (bRFS) in patients with intermediate or high-risk (HR) prostat...

    Authors: Zeina Ayoub, Jamal Khader, Muhammad Bulbul, Raja B. Khauli, Therese Y. Andraos, Ali Shamseddine, Deborah Mukherji and Fady B. Geara
    Citation: BMC Urology 2022 22:204
  21. As the main histological subtype of renal cell carcinoma, clear cell renal cell carcinoma (ccRCC) places a heavy burden on health worldwide. Autophagy-related long non-coding RNAs (ARlncRs) have shown tremendo...

    Authors: Fucai Tang, Zhicheng Tang, Zechao Lu, Yueqiao Cai, Yongchang Lai, Yuexue Mai, Zhibiao Li, Zeguang Lu, Jiahao Zhang, Ze Li and Zhaohui He
    Citation: BMC Urology 2022 22:203
  22. Authors: Zhengchao Liu, Zhipeng Chen, Dishi Yan, Tao Jiang, Jian Fu, Jun Zheng, Yuanxiu Zhou, Zhansong Zhou and Wenhao Shen
    Citation: BMC Urology 2022 22:199

    The original article was published in BMC Urology 2022 22:173

  23. Germline mutations represent a high risk of hereditary cancers in population. The landscape and characteristics of germline mutations in genitourinary cancer are largely unknown, and their correlation with pat...

    Authors: Yong Yang, Guoying Zhang, Chen Hu, Wei Luo, Haiyang Jiang, Shaoyou Liu and Hong Yang
    Citation: BMC Urology 2022 22:196
  24. Unpredicted postoperative recurrence of prostate cancer, one of the most common malignancies among males worldwide, has become a prominent issue affecting patients after treatment. Here, we investigated the co...

    Authors: Wenyan He, Furong Zhang, Feng Jiang, Huan Liu and Gang Wang
    Citation: BMC Urology 2022 22:195
  25. Noninvasively urine-based diagnostic modalities for upper urinary tract urothelial carcinoma (UTUC) were still lacking. We evaluated the diagnostic value of our previously developed urine-based assay (UTC assa...

    Authors: Xin Wang, Shiwei Zhang, Lang Wu, Baofu Feng, Hongwei Shen, Yuanyuan Gu, Qun Zhang, Feng Fang, Rong Yang and Hongqian Guo
    Citation: BMC Urology 2022 22:194
  26. To evaluate the incidence of positive cystic fluid cytology and its risk factors in cystic renal cell carcinoma (RCC) addressing its implication on the current surgical practice.

    Authors: Kyung Jae Hur, Qais Hooti, Dongho Shin, Yong Hyun Park, Woong Jin Bae, Hyukjin Cho, U-syn Ha, Ji Youl Lee, Yeong Jin Choi and Sung-Hoo Hong
    Citation: BMC Urology 2022 22:192
  27. More and more evidence showed that circRNA/miRNA/mRNA axis played a vital role in the pathogenesis of some diseases. However, the role of circRNA/miRNA/mRNA axis in partial bladder outlet obstruction (pBOO) re...

    Authors: Baoyi Zhu, Jun Gao, Yuying Zhang, Baojian Liao, Sihua Zhu, Chunling Li, Junhao Liao, Jianjia Liu, Chonghe Jiang and Jianwen Zeng
    Citation: BMC Urology 2022 22:191
  28. Hyperglycinuria is a rare disorder, with few reported cases, caused by either a defect in glycine metabolism or a disturbance in renal glycine reabsorption. Genetic findings of hyperglycinuria are rare and hav...

    Authors: Yang Pan, Shangren Wang, Li Liu and Xiaoqiang Liu
    Citation: BMC Urology 2022 22:190
  29. The high recurrence rate after traditional transurethral resection of bladder tumor (TURBT) remains a challenge for management of non-muscle invasive bladder tumor (NMIBC). The aim of this study was to evaluat...

    Authors: Lichen Teng, Changfu Li, Wentao Wang and Dechao Li
    Citation: BMC Urology 2022 22:189
  30. Urinary tract infections are among the most common indications for antibiotic therapy. The emergence of resistant uropathogens indicates the need for treatment alternatives. Replenishment of the glycosaminogly...

    Authors: M. S. Rahnama’i, A. Javan Balegh Marand, K. Röschmann-Doose, L. Steffens and H. J. Arendsen
    Citation: BMC Urology 2022 22:188
  31. Most patients with splenosis have no clinical symptoms and do not need intervention. Hematospermia and testicular pain occurred in this patient, which was considered to be related to the huge pelvic implantati...

    Authors: Yu Jiang, Lei Chen, Min Wang, Xiaocan Li, Dongdong Xie, Dexin Yu and Yi Wang
    Citation: BMC Urology 2022 22:187
  32. Soft tumors of the penis are extremely rare in childhood and adolescence. Because there are no guidelines, each such case raises embarrassment over the extent and degree of aggressiveness of the diagnostic and...

    Authors: Marcel Drlík, Mária Gregová, Josef Sedláček and Radim Kočvara
    Citation: BMC Urology 2022 22:186
  33. The American Joint Committee on Cancer (AJCC) 8th staging system of prostate cancer may be insufficient in predicting the prognosis of some staged patients. This study aimed to modify the AJCC 8th staging syst...

    Authors: Chengwen Sun, Dongrong Yang, Jin Zhu, Yibin Zhou, Congming Xiang and Sheng Wu
    Citation: BMC Urology 2022 22:185
  34. Despite the generally accepted World Health Organization guidelines on semen analysis, an individual’s results can display significant variation when performed across time or in different laboratories. Semen p...

    Authors: Yana Aznavour, Felipe Navarrete, Jad Badreddine, Paul H. G. Simon, Vrushab Gowda, Stephen Rhodes and Ramy Abou Ghayda
    Citation: BMC Urology 2022 22:184
  35. In this study, we investigated the ability of prostate-specific antigen (PSA) 12 months after (nPSA12) external beam radiotherapy (EBRT) combined with androgen deprivation therapy (ADT) to predict biochemical ...

    Authors: Ilknur Alsan Cetin, Sıtkı Utku Akay and Meric Sengoz
    Citation: BMC Urology 2022 22:182
  36. This study aimed to identify and validate the information content and functional capabilities of a smartphone-based application for the self-care of patients with urinary tract stones.

    Authors: Leila Shahmoradi, Amin Azizpour, Mahmud Bejani, Pejman Shadpour, Sorayya Rezayi, Jebraeil Farzi and Alireza Amanollahi
    Citation: BMC Urology 2022 22:181
  37. The retrospective observational study aimed to evaluate the safety and efficacy of suctioning flexible ureteroscopy with Intelligent pressure-control (SFUI) on treating upper urinary tract calculi in a large c...

    Authors: Xingjian Gao, Zedong Zhang, Xinwei Li, Weiping Cai, Bin Zheng, Yijin Lu, Hualong Zhao, Junhong You, Gangfeng Zheng, Weilong Bao, Yutong Lai and Yisong Lv
    Citation: BMC Urology 2022 22:180
  38. Situs inversus totalis is a very rare congenital anatomical variation, in which all thoracic and abdominal organs are right-left inverted. This condition is associated with an increased risk of organ malformat...

    Authors: Marah Mansour, Abdulmonem Naksho, Yassamine Ouerdane, Tamim Alsuliman, Hani Almozawer and Khaled Alrebdawi
    Citation: BMC Urology 2022 22:179
  39. Lower urinary tract symptoms (LUTS) are common among diabetic patients and represent hidden and mysterious morbidity. The pathophysiology of LUTS among diabetes mellitus (DM) patients is multifactorial. Import...

    Authors: Hala Qasrawi, Mahmoud Tabouni, Sara W. Almansour, Mohammad Ghannam, Amjad Abdalhaq, Faris Abushamma, Amer A. Koni and Sa’ed H. Zyoud
    Citation: BMC Urology 2022 22:178
  40. While gemcitabine/cisplatin (GC) is the gold standard regimen for patients with advanced urothelial carcinoma (aUC), either dose-reduced GC or gemcitabine/carboplatin (GCa) is an alternative option for “cispla...

    Authors: Kazuma Sugimoto, Satoru Taguchi, Kenjiro Kishitani, Taketo Kawai, Kazuki Masuda, Yu Nakamura, Manami Kinjo, Mitsuhiro Tambo, Jimpei Miyakawa, Yoshiyuki Akiyama, Yuta Yamada, Yusuke Sato, Daisuke Yamada, Tohru Nakagawa, Hiroshi Fukuhara and Haruki Kume
    Citation: BMC Urology 2022 22:177
  41. DNA methylation in cancer is considered a diagnostic and predictive biomarker. We investigated the usefulness of the methylation status of CALN1 as a biomarker for bladder cancer using methylation-sensitive restr...

    Authors: Kimiaki Takagi, Azumi Naruse, Kazutoshi Akita, Yuka Muramatsu-Maekawa, Kota Kawase, Takuya Koie, Masanobu Horie and Arizumi Kikuchi
    Citation: BMC Urology 2022 22:176
  42. This study aimed to evaluate the trend of adjuvant chemotherapy (AC) and neoadjuvant chemotherapy (NAC) in patients who underwent radical nephroureterectomy with bladder cuff excision (NUx) for upper tract uro...

    Authors: Jong Hyun Tae, Moon Soo Ha, Byung Hoon Chi, In Ho Chang, Tae-Hyoung Kim, Soon Chul Myung, Tuan Thanh Nguyen, Myoungsuk Kim, Kyung-Eun Lee, Yuwon Kim, Hyun-ki Woo, Dae-Sung Kyoung, Hasung Kim and Se Young Choi
    Citation: BMC Urology 2022 22:175

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