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  1. Due to their location away from the nerve bundles, anterior prostate cancers (APC) represent a rational target for image-guided cryoablation. This report describes the feasibility and short-term outcomes of an...

    Authors: Christina Sze, Efrat Tsivian, Kae Jack Tay, Ariel A. Schulman, Leah G. Davis, Rajan T. Gupta and Thomas J. Polascik

    Citation: BMC Urology 2019 19:127

    Content type: Research article

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  2. Bladder hyperthermic intracavitary chemotherapy (HIVEC) has good effectiveness for bladder cancer, but conventional HIVEC systems lack precision and convenient application. To test the safety of a new HIVEC de...

    Authors: Mingchen Ba, Shuzhong Cui, Hui Long, Yuanfeng Gong, Yinbing Wu, Kunpeng Lin, Yinuo Tu, Bahuo Zhang and Wanbo Wu

    Citation: BMC Urology 2019 19:126

    Content type: Research article

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  3. Second-line treatment for urothelial carcinoma (UC) patients is used if progression or failure after platinum-based chemotherapy occurs or if patients are cisplatin-unfit. However, there is still no widely acc...

    Authors: Huitao Wang, Jianhe Liu, Kewei Fang, Changxing Ke, Yongming Jiang, Guang Wang, Tongxin Yang, Tao Chen and Xin Shi

    Citation: BMC Urology 2019 19:125

    Content type: Research article

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  4. Identifying men for a repeat prostate biopsy is a conundrum to urologists. Risk calculators (RCs) such as the European Randomized Study of Screening for Prostate Cancer (ERSPC) RCs have been developed to predi...

    Authors: Pieter Minnee, Daphne Hessels, Jack A. Schalken and Wim Van Criekinge

    Citation: BMC Urology 2019 19:124

    Content type: Case report

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  5. Advances in systemic targeted therapies afford treatment opportunities in patients with metastatic renal cell carcinoma (RCC). Elderly patients with metastatic RCC present a subpopulation for consideration owi...

    Authors: Christopher S. Hollenbeak, Eric W. Schaefer, Justin Doan and Jay D. Raman

    Citation: BMC Urology 2019 19:123

    Content type: Research article

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  6. Accurate puncture and dilation of the target kidney calices for percutaneous nephrolithotomy (PCNL) can be difficult. This study aimed to investigate the advantages of PCNL using optical puncture (i.e. the pun...

    Authors: Mi Zhou, Xiang He, Yuelong Zhang and Weiwen Yu

    Citation: BMC Urology 2019 19:122

    Content type: Research article

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  7. Predictive models that take race into account like the Prostate Cancer Prevention Trial Risk Calculator 2.0 (PCPT RC) and the new Prostate Biopsy Collaborative Group (PBCG) RC have been developed to equitably ...

    Authors: Samuel Carbunaru, Oluwarotimi S. Nettey, Pooja Gogana, Irene B. Helenowski, Borko Jovanovic, Maria Ruden, Courtney M. P. Hollowell, Roohollah Sharifi, Rick A. Kittles, Edward Schaeffer, Peter Gann and Adam B. Murphy

    Citation: BMC Urology 2019 19:121

    Content type: Research article

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  8. Metabolic syndrome (MetS) and serum prostate-specific antigen (PSA) levels are correlated. To investigate the underlying effect of MetS on PSA levels, the relationship between the major pathogenic factors of M...

    Authors: Bo-Wen Xia, Si-Cong Zhao, Zong-Ping Chen, Chao Chen, Tian-Shu Liu, Fan Yang and Yong Yan

    Citation: BMC Urology 2019 19:119

    Content type: Research article

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  9. Pheochromocytoma is well-known for sudden initial presentations, particularly in younger patients. Hemodynamic instability may cause serious complications and delay a patient’s ability to undergo surgical rese...

    Authors: Umberto Maestroni, Francesco Ziglioli, Marco Baciarello, Valentina Bellini, Raffaele Dalla Valle, Simona Cataldo, Giada Maspero and Elena Bignami

    Citation: BMC Urology 2019 19:118

    Content type: Case report

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  10. Bladder cancer is a complex disease associated with high morbidity and mortality. Management of bladder cancer before radical cystectomy continues to be controversial. We compared the long-term efficacy of one...

    Authors: Wasilijiang Wahafu, Sai Liu, Wenbin Xu, Mengtong Wang, Qingbao He, Liming Song, Mingshuai Wang, Feiya Yang, Lin Hua, Yinong Niu and Nianzeng Xing

    Citation: BMC Urology 2019 19:117

    Content type: Research article

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  11. Pelvic floor muscle training (PFM) training for post-prostatectomy incontinence (PPI) is an important rehabilitative approach, but the evidence base is still evolving. We developed a novel PFM training program...

    Authors: Joanne E. Milios, Timothy R. Ackland and Daniel J. Green

    Citation: BMC Urology 2019 19:116

    Content type: Research article

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  12. Activation of mast cells plays an important role in the pathogenesis of bladder pain syndrome/interstitial cystitis (BPS/IC). Histamine, a mast cell-derived mediators, induced inflammation and hypersensitivity...

    Authors: Hui Shan, Er-Wei Zhang, Peng Zhang, Xiao-Dong Zhang, Ning Zhang, Peng Du and Yong Yang

    Citation: BMC Urology 2019 19:115

    Content type: Research article

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  13. Hypospadias are among the most common genital malformations. Langerhans Cells (LCs) play a pivotal role in HIV and HPV infection. The migration of LC precursors to skin coincides with the embryonic period of h...

    Authors: Bernhard Haid, Daniela Reider, Felix Nägele, Anne-Françoise Spinoit, Elisabeth Pechriggl, Nikolaus Romani, Helga Fritsch and Josef Oswald

    Citation: BMC Urology 2019 19:114

    Content type: Research article

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  14. Retzius-sparing robot-assisted laparoscopic radical prostatectomy (rsRARP) allows entire prostatectomy procedure via the pouch of Douglas. In low- and intermediate-risk prostate cancer (PCa) there is level 1 e...

    Authors: Joanne Nyaboe Nyarangi-Dix, Magdalena Görtz, Georgi Gradinarov, Luisa Hofer, Viktoria Schütz, Claudia Gasch, Jan Philipp Radtke and Markus Hohenfellner

    Citation: BMC Urology 2019 19:113

    Content type: Research article

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  15. Multiple surgical treatment options are available for the treatment of ureteropelvic junction obstruction (UPJO). The aim of this study is to compare the most frequently used technics in a comprehensive networ...

    Authors: Annemarie Uhlig, Johannes Uhlig, Lutz Trojan, Marc Hinterthaner, Alexander von Hammerstein-Equord and Arne Strauss

    Citation: BMC Urology 2019 19:112

    Content type: Research article

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  16. Micro-computerized tomography (micro-CT) is considered as an innovative non-invasive and high-resolution imaging technology. The current research aims to reconstruct the distribution of preputial vessels in di...

    Authors: Defu Lin, Pei Liu, Guannan Wang, Weiping Zhang and Ning Sun

    Citation: BMC Urology 2019 19:111

    Content type: Research article

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  17. Robot-assisted radical cystectomy is becoming a common treatment for bladder carcinoma. However, in comparison with open radical cystectomy, its cost-effectiveness has not been confirmed. Although few publishe...

    Authors: Yasuhiro Morii, Takahiro Osawa, Teppei Suzuki, Nobuo Shinohara, Toru Harabayashi, Tomoki Ishikawa, Takumi Tanikawa, Hiroko Yamashina and Katsuhiko Ogasawara

    Citation: BMC Urology 2019 19:110

    Content type: Research article

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  18. The prevalence of overactive bladder syndrome (OAB) increases with age. Sleep disturbances in elderly individuals with OAB is a common problem. The purpose of this study was to examine the effects of a biofeed...

    Authors: Jooyeon Park, Choal Hee Park, Sang-Eun Jun, Eun-Ju Lee, Seung Wan Kang and Nahyun Kim

    Citation: BMC Urology 2019 19:109

    Content type: Research article

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  19. Interstitial Cystitis (IC) is a debilitating disorder of the bladder, with a multifactorial and poorly understood origin dealing with microcirculation repeated damages. Also Fibromyalgia (FM) is a persistent d...

    Authors: Gerardo Bosco, Edoardo Ostardo, Alex Rizzato, Giacomo Garetto, Matteo Paganini, Giorgio Melloni, Giampiero Giron, Lodovico Pietrosanti, Ivo Martinelli and Enrico Camporesi

    Citation: BMC Urology 2019 19:108

    Content type: Research article

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  20. To report a new standardized cognitive fusion technique on transperineal targeted biopsy (TB) of prostate, and to evaluate its efficacy for cancer detection combined with systematic biopsy (SB) .

    Authors: Lei Wang, Xiaofei Wang, Wenfeng Zhao, Zichen Zhao, Zhihu Li, Shengmin Fei, He Zhu, Xiang Ji, Bing Yang, Ningchen Li and Yanqun Na

    Citation: BMC Urology 2019 19:107

    Content type: Research article

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  21. Benign prostatic hyperplasia (BPH) rarely occurs in children or young males. In this case report, a 29-year-old male patient diagnosed with BPH coexisting with ketamine-associated uropathy was reported to inve...

    Authors: Zhangcheng Liao, Zhao Wang, Zhongyuan Jin and Zhengyan Tang

    Citation: BMC Urology 2019 19:105

    Content type: Case report

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  22. Male genital skin loss is a common disease in urology. However, male genital skin loss accompanying a penile urethra defect is rarely reported. Herein, we describe a novel surgical technique using a composite ...

    Authors: Da-chao Zheng, Min-kai Xie, Shi-bo Fu, Jian-hua Guo, Wen-ji Li, Hai-jun Yao and Zhong Wang

    Citation: BMC Urology 2019 19:104

    Content type: Case report

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  23. Competent detrusor muscles with coordinated contraction and relaxation are crucial for normal urinary bladder storage and emptying functions. Hence, detrusor instability, and subsequently bladder overactivity,...

    Authors: Dalia F. El Agamy and Yahya M. Naguib

    Citation: BMC Urology 2019 19:103

    Content type: Research article

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  24. Laparoscopic adrenalectomy (LA) has become the “gold standard” for treating most adrenal tumors in the past decade. However, it is still considered a relatively complicated procedure requiring experience from ...

    Authors: Jadwiga Dworak, Michał Wysocki, Anna Rzepa, Michał Natkaniec, Michał Pędziwiatr, Andrzej Budzyński and Piotr Major

    Citation: BMC Urology 2019 19:102

    Content type: Research article

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  25. Prostate biopsy remains the gold standard approach to verify prostate cancer diagnosis. Transrectal (TR) biopsy is a regular modality, while transperineal (TP) biopsy is an alternative for the patients who dis...

    Authors: Guan-Lin Huang, Chih-Hsiung Kang, Wei-Ching Lee and Po-Hui Chiang

    Citation: BMC Urology 2019 19:101

    Content type: Research article

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  26. To evaluate the outcome and complication rate in a single institution experience using the two most commonly used techniques of ureteroenteric anastomosis, the Bricker and Wallace anastomosis.

    Authors: Frank Christoph, Franziska Herrmann, Peter Werthemann, Thomas Janik, Martin Schostak, Christian Klopf and Steffen Weikert

    Citation: BMC Urology 2019 19:100

    Content type: Research article

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  27. Chronic inflammation is thought to be a major causative factor for the development of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Tadalafil, a phosphodiesterase type 5 inhibitor...

    Authors: Mikio Sugimoto, Xia Zhang, Nobufumi Ueda, Hiroyuki Tsunemori, Rikiya Taoka, Yusi Hayashida, Hiromi Hirama, Yasuyuki Miyauchi, Yuki Matsuoka, Hirohito Naito, Yu Osaki and Yosiyuki Kekehi

    Citation: BMC Urology 2019 19:99

    Content type: Research article

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  28. Although the indications of minimally invasive treatments for pediatric urolithiasis are similar to those in adults, it is still crucial to make the right treatment decision due to the special considerations o...

    Authors: Qing He, Kaiwen Xiao, Yuntian Chen, Banghua Liao, Hong Li and Kunjie Wang

    Citation: BMC Urology 2019 19:98

    Content type: Research article

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  29. We investigated the surgical feasibility, safety and effectiveness of 50 W (low power) Holmium Laser enucleation of the prostate (HoLEP) in patients who have undergone previous template biopsy of the prostate ...

    Authors: Chris Bell, Sacha L. Moore, Amarit Gill, Obinna Obi-Njoku, Stephen F. Hughes, Asad Saleemi, Gidon Ellis, Farooq Khan and Iqbal S. Shergill

    Citation: BMC Urology 2019 19:97

    Content type: Research article

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  30. Robotic stereotactic ablative radiotherapy (SABR) is currently under investigation as a noninvasive treatment option for patients with renal cell carcinoma (RCC). For radiation therapy of RCC, tumor motion and...

    Authors: C. Senger, A. Conti, A. Kluge, D. Pasemann, M. Kufeld, G. Acker, M. Lukas, A. Grün, G. Kalinauskaite, V. Budach, J. Waiser and C. Stromberger

    Citation: BMC Urology 2019 19:96

    Content type: Research article

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  31. Electrical conductivity-based magnetic resonance (MR) imaging may provide unique information on tissue condition because its contrast originates from the concentration and mobility of ions in the cellular spac...

    Authors: Yong Soo Cho, Young Hoe Hur, Hyun Ju Seon, Jin Woong Kim and Hyung Joong Kim

    Citation: BMC Urology 2019 19:95

    Content type: Research article

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  32. Accurate grading at the time of diagnosis if fundamental to risk stratification and treatment decision making in patients with prostate cancer. Whilst previous studies have demonstrated significant pathologica...

    Authors: Nicholas Bullock, Andrew Simpkin, Sarah Fowler, Murali Varma, Howard Kynaston and Krishna Narahari

    Citation: BMC Urology 2019 19:94

    Content type: Research article

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  33. A supernumerary kidney (SK) is an additional kidney with its own capsule and blood supply that is not fused with the ipsilateral kidney (IK). Because individual case reports indicate a high morbidity rate, the...

    Authors: Peter Rehder, Rafael Rehwald, Julia M. Böhm, Astrid E. Grams, Alexander Loizides, Marco Pedrini, Jannik Stühmeier and Bernhard Glodny

    Citation: BMC Urology 2019 19:93

    Content type: Research article

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  34. Fatigue is one of the most prevalent symptoms among cancer patients. Specifically, in metastatic castration-resistant prostate cancer (mCRPC) patients, fatigue is the most common adverse event associated with ...

    Authors: A. Rodríguez Antolín, L. Martínez-Piñeiro, M. E. Jiménez Romero, J. B. García Ramos, D. López Bellido, J. Muñoz del Toro, A. García García-Porrero and F. Gómez Veiga

    Citation: BMC Urology 2019 19:92

    Content type: Research article

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  35. Neuroendocrine (NE) cells may have an impact on the development and initial growth of benign prostatic hyperplasia (BPH) according to previous human studies.

    Authors: Yuki Kyoda, Koji Ichihara, Kohei Hashimoto, Ko Kobayashi, Fumimasa Fukuta and Naoya Masumori

    Citation: BMC Urology 2019 19:91

    Content type: Research article

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  36. Because of the failure, shortage and related toxicities of Bacillus Calmette-Guérin (BCG), the other intravesical chemotherapy drugs are also widely used in clinical application. Gemcitabine and anthracycline ...

    Authors: Tian-Wei Wang, Hui Yuan, Wen-Li Diao, Rong Yang, Xiao-Zhi Zhao and Hong-Qian Guo

    Citation: BMC Urology 2019 19:90

    Content type: Research article

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  37. A variety of penile rehabilitation (PR) therapies are available to improve post-prostatectomy erectile dysfunction (ED) with mixed results. It is uncertain how adherent men are to PR therapies. The aim of this...

    Authors: Jeffrey Albaugh, Brittany Adamic, Cecilia Chang, Nicholas Kirwen and Joshua Aizen

    Citation: BMC Urology 2019 19:89

    Content type: Research article

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  38. The association between surgical outcome of hypospadias repair and long-term male reproductive function has not been documented. The purpose of this study was to clarify association between paternity in adult ...

    Authors: Akihiro Kanematsu, Shiro Tanaka, Takahiko Hashimoto, Michio Nojima and Shingo Yamamoto

    Citation: BMC Urology 2019 19:88

    Content type: Research article

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  39. We investigated the impact of postoperative membranous urethral length and other anatomic characteristics of the pelvic floor shape as measured by magnetic resonance imaging on the improvement in continence fo...

    Authors: Akihiro Nakane, Hiroki Kubota, Yusuke Noda, Tomoki Takeda, Yasuhiko Hirose, Atsushi Okada, Kentaro Mizuno, Noriyasu Kawai, Keiichi Tozawa, Yutaro Hayashi and Takahiro Yasui

    Citation: BMC Urology 2019 19:87

    Content type: Research article

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  40. Despite international recommendations of including patient-reported outcomes (PROs) in randomised clinical trials (RCTs), a 2014 review concluded that few RCTs of bladder cancer (BC) report PRO as an outcome. ...

    Authors: Mieke Van Hemelrijck, Francesco Sparano, Debra Josephs, Mirjam Sprangers, Francesco Cottone and Fabio Efficace

    Citation: BMC Urology 2019 19:86

    Content type: Research article

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  41. There is an increased incidence of renal cell carcinoma (RCC) in patients with metabolic syndrome who usually have high levels of serum triglyceride (TG) and low high-density lipoprotein-cholesterol (HDL-C). P...

    Authors: Emre Karabay, Nejdet Karsiyakali, Serdar Duvar, Cagatay Tosun, Ahmet Ruknettin Aslan and Omer Ergin Yucebas

    Citation: BMC Urology 2019 19:85

    Content type: Research article

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  42. In patients presenting with limited nodal recurrence following radical prostatectomy (RP), stereotactic body radiotherapy (SBRT) results might improve with a better case selection.

    Authors: Christoph Oehler, Michel Zimmermann, Lukas Adam, Juergen Curschmann, Marcin Sumila, Räto T. Strebel, Richard Cathomas, Qiyu Li, Uwe Schneider and Daniel R. Zwahlen

    Citation: BMC Urology 2019 19:84

    Content type: Research article

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  43. We aimed to investigate the prevalence, relative risk factors, and the impact on the health-related quality of life (HRQoL) of benign prostatic obstruction (BPO) with coexisting overactive bladder (OAB) in men...

    Authors: Qing-Tong Yi, Min Gong, Chu-Hong Chen, Wei Hu and Ru-Jian Zhu

    Citation: BMC Urology 2019 19:82

    Content type: Research article

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  44. To compare quality of life (QoL) indices between ureteral stent (DJS) and nephrostomy tube (PCN) inserted in the setting of acute ureteral obstruction.

    Authors: O. Shoshany, T. Erlich, S. Golan, N. Kleinmann, J. Baniel, B. Rosenzweig, A. Eisner, Y. Mor, J. Ramon, H. Winkler and D. Lifshitz

    Citation: BMC Urology 2019 19:79

    Content type: Research article

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  45. Lower urinary tract symptoms (LUTS) is the most common complication of diabetes. However, the underlying pathogenesis of cultured negative LUTS (cn-LUTS) in diabetic patients has not been well understood. Nume...

    Authors: Jiawei Chen, Jie Zhao, Ying Cao, Guihao Zhang, Yang Chen, Jialei Zhong, Weina Huang, Jiarong Zeng and Peng Wu

    Citation: BMC Urology 2019 19:78

    Content type: Research article

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